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Gene

TLE2

TLE family member 2, transcriptional corepressor

Summary

Cytogenetic location
19p13.3
Coordinates
Chromosome 19: 2,997,644–3,029,280 (GRCh38)
Exons
20 exons across 31.6 kb
Protein
743 amino acids
Also known as
ESG2, GRG2, ESG, FLJ41188
MANE Select transcript
ENST00000262953.11NM_003260.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TLE2 yet. The test sequences your whole genome, so your data includes it all the same.

How TLE2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 19, with a bracket where TLE2 sits. TLE2 and 23 genes near it on chromosome 19, from 2,513,462 to 3,513,461.Chromosome 1919p13.3p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.432.6 Mb2.8 Mb3 Mb3.2 Mb3.4 MbGNG7: 2,511,214–2,702,727, reverse strandGNG7DIRAS1: 2,714,566–2,721,438, reverse strandDIRAS1: 2,717,769–2,740,048, reverse strandSLC39A3: 2,732,204–2,740,071, reverse strandSLC39A3SGTA: 2,754,711–2,783,390, reverse strandSGTATHOP1: 2,785,444–2,815,807, forward strandTHOP1ZNF554: 2,819,853–2,836,735, forward strandZNF554ZNF555: 2,841,437–2,860,471, forward strandZNF555ZNF556: 2,867,292–2,883,445, forward strandZNF556ZNF57: 2,900,914–2,919,102, forward strandZNF57ZNF77: 2,931,137–2,944,971, reverse strandZNF77TLE6: 2,977,538–2,995,179, forward strandTLE6TLE2: 2,997,644–3,029,280, reverse strandTLE2TLE5: 3,052,908–3,063,112, reverse strandTLE5GNA11: 3,094,320–3,124,001, forward strandGNA11GNA15: 3,136,027–3,163,749, forward strandGNA15S1PR4: 3,172,346–3,180,332, forward strandS1PR4NCLN: 3,185,563–3,209,575, forward strandNCLNCELF5: 3,224,636–3,297,076, forward strandCELF5NFIC: 3,314,403–3,469,217, forward strandNFICSMIM24: 3,473,986–3,480,557, reverse strandSMIM24SMIM44: 3,482,110–3,483,441, reverse strandSMIM44DOHH: 3,490,821–3,507,203, reverse strandDOHHFZR1: 3,506,270–3,538,334, forward strandFZR1Diagram of TLE2: 20 exons on the reverse strand of chromosome 19Exon 20: 2,997,644–2,997,955, 312 basesExon 19: 3,000,647–3,000,723, 77 basesExon 18: 3,002,353–3,002,503, 151 basesExon 17: 3,005,437–3,005,584, 148 basesExon 16: 3,005,721–3,005,968, 248 basesExon 15: 3,006,420–3,006,669, 250 basesExon 14: 3,008,869–3,008,945, 77 basesExon 13: 3,009,542–3,009,702, 161 basesExon 12: 3,011,022–3,011,160, 139 basesExon 11: 3,013,669–3,013,818, 150 basesExon 10: 3,014,570–3,014,614, 45 basesExon 9: 3,015,653–3,015,760, 108 basesExon 8: 3,017,840–3,017,859, 20 basesExon 7: 3,019,283–3,019,463, 181 basesExon 6: 3,019,699–3,019,773, 75 basesExon 5: 3,025,020–3,025,082, 63 basesExon 4: 3,027,829–3,027,873, 45 basesExon 3: 3,028,319–3,028,382, 64 basesExon 2: 3,028,706–3,028,803, 98 basesExon 1: 3,028,881–3,029,280, 400 bases201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.8 kb of the gene's 31.6 kb; 2,232 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TLE2 gene: TLE family member 2, transcriptional corepressor. Retrieved 17 October 2026, from https://dantelabs.com/genes/tle2

Vancouver

Dante Labs. TLE2 gene: TLE family member 2, transcriptional corepressor [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tle2

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