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Gene

NR1H3

nuclear receptor subfamily 1 group H member 3

Summary

Cytogenetic location
11p11.2
Coordinates
Chromosome 11: 47,257,996–47,269,033 (GRCh38)
Exons
10 exons across 11 kb
Protein
447 amino acids
Also known as
LXR-a, RLD-1, LXRa
MANE Select transcript
ENST00000441012.7NM_005693.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NR1H3 yet. The test sequences your whole genome, so your data includes it all the same.

How NR1H3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where NR1H3 sits. NR1H3 and 23 genes near it on chromosome 11, from 46,763,515 to 47,763,514.Chromosome 1111p11.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2546.8 Mb47 Mb47.2 Mb47.4 Mb47.6 MbF2: 46,719,079–46,768,566, forward strandF2CKAP5: 46,742,768–46,846,308, reverse strandCKAP5LRP4: 46,856,717–46,918,642, reverse strandLRP4CSTPP1: 46,936,689–47,165,535, forward strandCSTPP1ARFGAP2: 47,135,667–47,177,474, reverse strandARFGAP2PACSIN3: 47,177,511–47,187,487, reverse strandPACSIN3DDB2: 47,214,435–47,240,555, forward strandDDB2ACP2: 47,237,598–47,249,288, reverse strandACP2NR1H3: 47,257,996–47,269,033, forward strandNR1H3MADD: 47,269,161–47,330,038, forward strandMADDMYBPC3: 47,331,406–47,352,702, reverse strandMYBPC3SPI1: 47,354,860–47,409,369, reverse strandSPI1SLC39A13: 47,407,132–47,416,587, forward strandSLC39A13PSMC3: 47,418,765–47,426,488, reverse strandPSMC3RAPSN: 47,436,816–47,449,192, reverse strandRAPSNCELF1: 47,465,933–47,565,569, reverse strandCELF1NDUFS3: 47,565,336–47,584,565, forward strandNDUFS3PTPMT1: 47,565,430–47,573,461, forward strandPTPMT1KBTBD4: 47,572,196–47,578,982, reverse strandKBTBD4FAM180B: 47,586,207–47,589,195, forward strandC1QTNF4: 47,589,666–47,595,642, reverse strandMTCH2: 47,604,339–47,642,698, reverse strandAGBL2: 47,659,591–47,715,389, reverse strandAGBL2FNBP4: 47,716,494–47,767,460, reverse strandFNBP4Diagram of NR1H3: 10 exons on the forward strand of chromosome 11Exon 1: 47,257,996–47,258,129, 134 basesExon 2: 47,259,180–47,259,259, 80 basesExon 3: 47,259,791–47,259,979, 189 basesExon 4: 47,260,409–47,260,675, 267 basesExon 5: 47,261,241–47,261,449, 209 basesExon 6: 47,261,547–47,261,726, 180 basesExon 7: 47,261,919–47,262,018, 100 basesExon 8: 47,267,913–47,268,026, 114 basesExon 9: 47,268,261–47,268,355, 95 basesExon 10: 47,268,550–47,269,033, 484 bases123456789105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.9 kb of the gene's 11 kb; 1,344 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). NR1H3 gene: nuclear receptor subfamily 1 group H member 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/nr1h3

Vancouver

Dante Labs. NR1H3 gene: nuclear receptor subfamily 1 group H member 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/nr1h3

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