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Gene

CPSF3

cleavage and polyadenylation specific factor 3

Summary

Cytogenetic location
2p25.1
Coordinates
Chromosome 2: 9,423,654–9,473,101 (GRCh38)
Exons
18 exons across 49.4 kb
Protein
684 amino acids
Also known as
CPSF-73, CPSF73, YSH1
MANE Select transcript
ENST00000238112.8NM_016207.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CPSF3 yet. The test sequences your whole genome, so your data includes it all the same.

How CPSF3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where CPSF3 sits. CPSF3 and 7 genes near it on chromosome 2, from 8,948,378 to 9,948,377.Chromosome 22p25.1p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.39 Mb9.2 Mb9.4 Mb9.6 Mb9.8 MbMBOAT2: 8,852,473–9,003,859, reverse strandMBOAT2ASAP2: 9,206,602–9,405,683, forward strandASAP2ITGB1BP1: 9,402,707–9,423,891, reverse strandITGB1BP1CPSF3: 9,423,654–9,473,101, forward strandCPSF3IAH1: 9,473,658–9,500,587, forward strandIAH1ADAM17: 9,488,482–9,556,732, reverse strandADAM17YWHAQ: 9,583,334–9,639,472, reverse strandYWHAQTAF1B: 9,843,340–9,934,994, forward strandTAF1BDiagram of CPSF3: 18 exons on the forward strand of chromosome 2Exon 1: 9,423,654–9,423,823, 170 basesExon 2: 9,428,765–9,428,828, 64 basesExon 3: 9,429,923–9,430,020, 98 basesExon 4: 9,430,752–9,430,880, 129 basesExon 5: 9,432,511–9,432,688, 178 basesExon 6: 9,433,871–9,433,960, 90 basesExon 7: 9,436,211–9,436,361, 151 basesExon 8: 9,440,491–9,440,666, 176 basesExon 9: 9,441,818–9,441,976, 159 basesExon 10: 9,443,515–9,443,661, 147 basesExon 11: 9,448,198–9,448,350, 153 basesExon 12: 9,452,913–9,453,021, 109 basesExon 13: 9,455,659–9,455,757, 99 basesExon 14: 9,456,933–9,457,027, 95 basesExon 15: 9,459,531–9,459,618, 88 basesExon 16: 9,467,707–9,467,776, 70 basesExon 17: 9,471,343–9,471,439, 97 basesExon 18: 9,472,916–9,473,101, 186 bases1234567891011121314151617185′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.3 kb of the gene's 49.4 kb; 2,055 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). CPSF3 gene: cleavage and polyadenylation specific factor 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/cpsf3

Vancouver

Dante Labs. CPSF3 gene: cleavage and polyadenylation specific factor 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/cpsf3

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