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Gene

CLIC5

CLIC family member 5

Summary

Cytogenetic location
6p21.1
Coordinates
Chromosome 6: 45,898,456–46,015,860 (GRCh38)
Exons
6 exons across 117.4 kb
Protein
251 amino acids
Also known as
DFNB102
MANE Select transcript
ENST00000339561.12NM_016929.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CLIC5 yet. The test sequences your whole genome, so your data includes it all the same.

How CLIC5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 6, with a bracket where CLIC5 sits. CLIC5 and 4 genes near it on chromosome 6, from 45,457,158 to 46,457,157.Chromosome 66p21.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2745.6 Mb45.8 Mb46 Mb46.2 Mb46.4 MbRUNX2: 45,328,157–45,664,349, forward strandRUNX2CLIC5: 45,898,456–46,015,860, reverse strandCLIC5ENPP4: 46,129,959–46,152,554, forward strandENPP4ENPP5: 46,149,704–46,171,113, reverse strandENPP5RCAN2: 46,220,718–46,491,972, reverse strandRCAN2Diagram of CLIC5: 6 exons on the reverse strand of chromosome 6Exon 5: 1 known disease-causing siteExon 6: 45,898,456–45,903,255, 4,800 basesExon 5: 45,914,228–45,914,409, 182 basesExon 4: 45,941,547–45,941,653, 107 basesExon 3: 45,949,256–45,949,381, 126 basesExon 2: 45,955,135–45,955,244, 110 basesExon 1: 46,015,480–46,015,860, 381 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.7 kb of the gene's 117.4 kb; 756 of those bases code for the protein.

How a genome test reads CLIC5

1

position in CLIC5 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 117.4 kb of CLIC5, introns included, not only the 5.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CLIC5 gene: CLIC family member 5. Retrieved 17 October 2026, from https://dantelabs.com/genes/clic5

Vancouver

Dante Labs. CLIC5 gene: CLIC family member 5 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/clic5

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