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Trait

Selective mutism

Voluntary failure to use spoken language (at whatever level attained) in selective social contexts over a period of time.

HPO HP:5200001

Summary

Body system
Abnormality of the nervous system

2 genes linked to Selective mutism

Changes in these genes cause rare conditions in which Selective mutism is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
LRRC7leucine rich repeat containing 7AlwaysIn 1 condition
AXIN1axin 1Sometimes (5–29%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

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Broader traits

Inability to speak

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

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