Trait

Pseudohypoaldosteronism

A state of renal tubular unresponsiveness or resistance to the action of aldosterone.

Body system: Abnormality of the endocrine system

This page as data

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library(jsonlite)

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page <- fromJSON(url)
page$trait$name

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6 genes linked to Pseudohypoaldosteronism

Changes in these genes cause rare conditions in which Pseudohypoaldosteronism is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
CUL3cullin 3	Not recorded	In 1 condition
KLHL3kelch like family member 3	Not recorded	In 1 condition
NR3C2nuclear receptor subfamily 3 group C member 2	Not recorded	In 1 condition
SCNN1Asodium channel epithelial 1 subunit alpha	Not recorded	In 1 condition
WNK1WNK lysine deficient protein kinase 1	Not recorded	In 1 condition
WNK4WNK lysine deficient protein kinase 4	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormality of adrenal physiology

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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