{
  "url": "https://dantelabs.com/traits/pseudohypoaldosteronism",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "pseudohypoaldosteronism",
    "id": "HP:0008242",
    "name": "Pseudohypoaldosteronism",
    "definition": "A state of renal tubular unresponsiveness or resistance to the action of aldosterone.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-adrenal-physiology",
        "name": "Abnormality of adrenal physiology",
        "url": "https://dantelabs.com/traits/abnormality-of-adrenal-physiology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cul3",
        "symbol": "CUL3",
        "hgnc": "HGNC:2553",
        "name": "cullin 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cul3"
      },
      {
        "slug": "klhl3",
        "symbol": "KLHL3",
        "hgnc": "HGNC:6354",
        "name": "kelch like family member 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/klhl3"
      },
      {
        "slug": "nr3c2",
        "symbol": "NR3C2",
        "hgnc": "HGNC:7979",
        "name": "nuclear receptor subfamily 3 group C member 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr3c2"
      },
      {
        "slug": "scnn1a",
        "symbol": "SCNN1A",
        "hgnc": "HGNC:10599",
        "name": "sodium channel epithelial 1 subunit alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scnn1a"
      },
      {
        "slug": "wnk1",
        "symbol": "WNK1",
        "hgnc": "HGNC:14540",
        "name": "WNK lysine deficient protein kinase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnk1"
      },
      {
        "slug": "wnk4",
        "symbol": "WNK4",
        "hgnc": "HGNC:14544",
        "name": "WNK lysine deficient protein kinase 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnk4"
      }
    ]
  }
}