Trait
Generalized swelling of lymph nodes
Clinical name: Generalized lymphadenopathy
A generalized form of lymphadenopathy.
Summary
- Also called
- Swollen lymph nodes affecting all regions of the body, Generalised lymphadenopathy, Generalised swelling of lymph nodes
Reference genomeGRCh38hg38
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Read the genes linked to Generalized swelling of lymph nodes, and the rest of your genome, with one test.
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Get my Genome Test14 genes linked to Generalized swelling of lymph nodes
Changes in these genes cause rare conditions in which Generalized swelling of lymph nodes is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AK2adenylate kinase 2 | Always | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Always | In 2 conditions |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Always | In 1 condition |
| LRBALPS responsive beige-like anchor protein | Always | In 1 condition |
| NFATC2nuclear factor of activated T cells 2 | Always | In 1 condition |
| PRKCDprotein kinase C delta | Always | In 1 condition |
| RAC2Rac family small GTPase 2 | Always | In 1 condition |
| RAG1recombination activating 1 | Always | In 1 condition |
| RAG2recombination activating 2 | Always | In 1 condition |
| TNFRSF9TNF receptor superfamily member 9 | Always | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Sometimes (5–29%) | In 1 condition |
| RNF168ring finger protein 168 | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Not recorded | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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