Trait
Generalized ichthyosis
Summary
- Also called
- Generalised ichthyosis
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test6 genes linked to Generalized ichthyosis
Changes in these genes cause rare conditions in which Generalized ichthyosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| NIPAL4NIPA like domain containing 4 | Always | In 1 condition |
| PNPLA1patatin like domain 1, omega-hydroxyceramide transacylase | Always | In 1 condition |
| SLC27A4solute carrier family 27 member 4 | Always | In 1 condition |
| ALDH3A2aldehyde dehydrogenase 3 family member A2 | Very often (80–99%) | In 1 condition |
| LORICRINloricrin cornified envelope precursor protein | Very often (80–99%) | In 1 condition |
| PHGDHphosphoglycerate dehydrogenase | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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