Trait

Episodic pain

Intermittent pain, i.e., pain that occurs occasionally and at irregular intervals.

HPO HP:0032148

Body system: Constitutional symptom

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3 genes linked to Episodic pain

Changes in these genes cause rare conditions in which Episodic pain is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
TGFBItransforming growth factor beta induced	Often (30–79%)	In 1 condition
LEMD3LEM domain containing 3	Sometimes (5–29%)	In 1 condition
TRPA1transient receptor potential cation channel subfamily A member 1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Intermittent abdominal pain37 genes

Broader traits

Pain

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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