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Trait

Conspicuously happy disposition

An unusually happy demeanor over time, which can also be observed during inappropriate situations that should, for example, cause distress, fear, or anger.

HPO HP:0100024

Summary

Also called
Conspicious happy aspect, Happy aspect
Body system
Abnormality of the nervous system

3 condition reports read genes linked to this trait

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5 genes linked to Conspicuously happy disposition

Changes in these genes cause rare conditions in which Conspicuously happy disposition is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
KANSL1KAT8 regulatory NSL complex subunit 1Very often (80–99%)In 1 condition
SLC9A6solute carrier family 9 member A6Often (30–79%)In 1 condition
HNRNPH2heterogeneous nuclear ribonucleoprotein H2Sometimes (5–29%)In 1 condition
SATB2SATB homeobox 2Sometimes (5–29%)In 1 condition
SIN3ASIN3 transcription regulator family member ANot recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Happy demeanor

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.19-9814e911.

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