Trait
Coldness
Relative coldness of a body part to palpitation, often acccompanied by feelings of coldness.
Summary
- Also called
- Cold skin temperature, Cool skin, Cool skin temperature, Coolness to palpation
- Body system
- Constitutional symptom
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test8 genes linked to Coldness
Changes in these genes cause rare conditions in which Coldness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CDKL5cyclin dependent kinase like 5 | Often (30–79%) | In 1 condition |
| FOXE1forkhead box E1 | Often (30–79%) | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Often (30–79%) | In 1 condition |
| NKX2-1NK2 homeobox 1 | Often (30–79%) | In 1 condition |
| NKX2-5NK2 homeobox 5 | Often (30–79%) | In 1 condition |
| PAX8paired box 8 | Often (30–79%) | In 1 condition |
| SLC26A4solute carrier family 26 member 4 | Often (30–79%) | In 1 condition |
| TSHRthyroid stimulating hormone receptor | Often (30–79%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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