Trait
Calvarial osteosclerosis
An increase in bone density affecting the calvaria (roof of the skull).
Summary
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Calvarial osteosclerosis, and the rest of your genome, with one test.
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Get my Genome Test8 genes linked to Calvarial osteosclerosis
Changes in these genes cause rare conditions in which Calvarial osteosclerosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DVL1dishevelled segment polarity protein 1 | Always | In 1 condition |
| KLklotho | Always | In 1 condition |
| TCIRG1T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | Always | In 1 condition |
| FAM111AFAM111 trypsin like peptidase A | Often (30–79%) | In 1 condition |
| LRP5LDL receptor related protein 5 | Often (30–79%) | In 1 condition |
| TBCEtubulin folding cofactor E | Often (30–79%) | In 2 conditions |
| AP1S2adaptor related protein complex 1 subunit sigma 2 | Sometimes (5–29%) | In 1 condition |
| ANKHANKH inorganic pyrophosphate transport regulator | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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