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Gene

YAP1

Yes1 associated transcriptional regulator

Summary

Cytogenetic location
11q22.1
Coordinates
Chromosome 11: 102,110,447–102,233,424 (GRCh38)
Exons
9 exons across 123 kb
Protein
504 amino acids
Also known as
YAP65, YAP-1
MANE Select transcript
ENST00000282441.10NM_001130145.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads YAP1 yet. The test sequences your whole genome, so your data includes it all the same.

How YAP1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where YAP1 sits. YAP1 and 9 genes near it on chromosome 11, from 101,671,936 to 102,671,935.Chromosome 1111q22.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25101.8 Mb102 Mb102.2 Mb102.4 Mb102.6 MbTRPC6: 101,447,437–101,872,562, reverse strandTRPC6ANGPTL5: 101,890,660–102,026,456, reverse strandANGPTL5CEP126: 101,914,997–102,001,062, forward strandCEP126CFAP300: 102,047,402–102,085,137, forward strandCFAP300YAP1: 102,110,447–102,233,424, forward strandYAP1BIRC3: 102,317,451–102,339,403, forward strandBIRC3BIRC2: 102,347,208–102,378,680, forward strandBIRC2TMEM123: 102,396,329–102,470,384, reverse strandTMEM123MMP7: 102,520,508–102,530,853, reverse strandMMP7MMP20: 102,576,832–102,625,332, reverse strandMMP20Diagram of YAP1: 9 exons on the forward strand of chromosome 11Exon 1: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 1: 102,110,447–102,111,169, 723 basesExon 2: 102,114,144–102,114,394, 251 basesExon 3: 102,162,456–102,162,571, 116 basesExon 4: 102,186,018–102,186,131, 114 basesExon 5: 102,205,893–102,206,074, 182 basesExon 6: 102,209,517–102,209,564, 48 basesExon 7: 102,223,622–102,223,752, 131 basesExon 8: 102,227,469–102,227,581, 113 basesExon 9: 102,229,702–102,233,424, 3,723 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.4 kb of the gene's 123 kb; 1,515 of those bases code for the protein.

How a genome test reads YAP1

3

positions in YAP1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 123 kb of YAP1, introns included, not only the 5.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). YAP1 gene: Yes1 associated transcriptional regulator. Retrieved 16 October 2026, from https://dantelabs.com/genes/yap1

Vancouver

Dante Labs. YAP1 gene: Yes1 associated transcriptional regulator [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/yap1

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