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Gene

TBX21

T-box transcription factor 21

Summary

Cytogenetic location
17q21.32
Coordinates
Chromosome 17: 47,733,236–47,746,122 (GRCh38)
Exons
6 exons across 12.9 kb
Protein
535 amino acids
Also known as
TBLYM, T-bet
MANE Select transcript
ENST00000177694.2NM_013351.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TBX21 yet. The test sequences your whole genome, so your data includes it all the same.

How TBX21 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where TBX21 sits. TBX21 and 20 genes near it on chromosome 17, from 47,239,679 to 48,239,678.Chromosome 1717q21.32p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.347.4 Mb47.6 Mb47.8 Mb48 Mb48.2 MbITGB3: 47,253,649–47,323,218, forward strandITGB3: 47,253,897–47,344,292, forward strandEFCAB13: 47,323,290–47,441,312, forward strandEFCAB13NPEPPS: 47,522,942–47,624,707, forward strandNPEPPSKPNB1: 47,649,476–47,685,505, forward strandKPNB1TBKBP1: 47,694,030–47,712,063, forward strandTBKBP1TBX21: 47,733,236–47,746,122, forward strandTBX21OSBPL7: 47,807,363–47,821,890, reverse strandOSBPL7MRPL10: 47,823,272–47,831,545, reverse strandMRPL10LRRC46: 47,831,634–47,837,719, forward strandLRRC46SCRN2: 47,837,683–47,842,125, reverse strandSCRN2SP6: 47,844,908–47,855,874, reverse strandSP2: 47,896,150–47,928,964, forward strandSP2PNPO: 47,941,506–47,964,354, forward strandPNPOPRR15L: 47,950,851–47,960,483, reverse strandPRR15LCDK5RAP3: 47,967,810–47,981,787, forward strandCDK5RAP3COPZ2: 48,026,142–48,038,030, reverse strandCOPZ2NFE2L1: 48,047,889–48,088,647, forward strandNFE2L1CBX1: 48,070,052–48,107,848, reverse strandCBX1SNX11: 48,103,357–48,128,226, forward strandSNX11SKAP1: 48,133,433–48,430,275, reverse strandSKAP1Diagram of TBX21: 6 exons on the forward strand of chromosome 17Exon 1: 47,733,236–47,733,945, 710 basesExon 2: 47,742,610–47,742,764, 155 basesExon 3: 47,743,071–47,743,192, 122 basesExon 4: 47,744,195–47,744,353, 159 basesExon 5: 47,744,482–47,744,543, 62 basesExon 6: 47,744,748–47,746,122, 1,375 bases1234565′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.6 kb of the gene's 12.9 kb; 1,608 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). TBX21 gene: T-box transcription factor 21. Retrieved 17 October 2026, from https://dantelabs.com/genes/tbx21

Vancouver

Dante Labs. TBX21 gene: T-box transcription factor 21 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tbx21

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