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Gene

SREBF2

sterol regulatory element binding transcription factor 2

Summary

Cytogenetic location
22q13.2
Coordinates
Chromosome 22: 41,833,105–41,907,305 (GRCh38)
Exons
19 exons across 74.2 kb
Protein
1,141 amino acids
Also known as
SREBP2, bHLHd2
MANE Select transcript
ENST00000361204.9NM_004599.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SREBF2 yet. The test sequences your whole genome, so your data includes it all the same.

How SREBF2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 22, with a bracket where SREBF2 sits. SREBF2 and 25 genes near it on chromosome 22, from 41,370,205 to 42,370,204.Chromosome 2222q13.2p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3341.4 Mb41.6 Mb41.8 Mb42 Mb42.2 MbTEF: 41,367,333–41,399,326, forward strandTEFTOB2: 41,433,489–41,447,602, reverse strandTOB2ACO2: 41,447,830–41,529,273, forward strandACO2PHF5A: 41,448,895–41,468,713, reverse strandPHF5APOLR3H: 41,525,799–41,544,606, reverse strandPOLR3HCSDC2: 41,560,758–41,577,741, forward strandCSDC2PMM1: 41,576,886–41,595,275, reverse strandPMM1DESI1: 41,598,028–41,621,089, reverse strandDESI1XRCC6: 41,620,786–41,664,087, forward strandXRCC6SNU13: 41,666,627–41,690,504, reverse strandSNU13MEI1: 41,699,494–41,799,456, forward strandMEI1CCDC134: 41,800,321–41,832,178, forward strandCCDC134SREBF2: 41,833,105–41,907,305, forward strandSREBF2SHISA8: 41,906,316–41,915,129, reverse strandSHISA8TNFRSF13C: 41,922,032–41,926,806, reverse strandTNFRSF13CCENPM: 41,927,514–41,947,183, reverse strandCENPMSMIM45: 41,947,178–41,958,942, forward strandSMIM45SEPTIN3: 41,969,443–41,998,221, forward strandSEPTIN3WBP2NL: 41,998,725–42,058,456, forward strandWBP2NLNAGA: 42,032,595–42,071,198, reverse strandNAGAPHETA2: 42,073,789–42,079,439, forward strandPHETA2SMDT1: 42,079,564–42,090,033, forward strandSMDT1NDUFA6: 42,080,336–42,090,884, reverse strandCYP2D6: 42,120,962–42,131,727, reverse strandCYP2D6CYP2D7: 42,140,203–42,149,500, reverse strandCYP2D7TCF20: 42,160,013–42,343,616, reverse strandTCF20Diagram of SREBF2: 19 exons on the forward strand of chromosome 22Exon 1: 41,833,105–41,833,358, 254 basesExon 2: 41,866,831–41,867,280, 450 basesExon 3: 41,868,611–41,868,792, 182 basesExon 4: 41,870,889–41,871,035, 147 basesExon 5: 41,873,798–41,874,019, 222 basesExon 6: 41,875,337–41,875,451, 115 basesExon 7: 41,875,543–41,875,724, 182 basesExon 8: 41,877,229–41,877,421, 193 basesExon 9: 41,877,942–41,878,123, 182 basesExon 10: 41,880,716–41,880,992, 277 basesExon 11: 41,884,842–41,885,011, 170 basesExon 12: 41,893,117–41,893,285, 169 basesExon 13: 41,894,820–41,894,937, 118 basesExon 14: 41,897,052–41,897,161, 110 basesExon 15: 41,898,649–41,898,781, 133 basesExon 16: 41,900,330–41,900,498, 169 basesExon 17: 41,902,970–41,903,155, 186 basesExon 18: 41,904,863–41,904,974, 112 basesExon 19: 41,905,440–41,907,305, 1,866 bases151015195′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.2 kb of the gene's 74.2 kb; 3,426 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SREBF2 gene: sterol regulatory element binding transcription factor 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/srebf2

Vancouver

Dante Labs. SREBF2 gene: sterol regulatory element binding transcription factor 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/srebf2

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