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Gene

TOB2

transducer of ERBB2, 2

Summary

Cytogenetic location
22q13.2
Coordinates
Chromosome 22: 41,433,494–41,446,801 (GRCh38)
Exons
2 exons across 13.3 kb
Protein
344 amino acids
Also known as
TOBL, TOB4, bK223H9, APRO5
Previous symbols
TROB2
MANE Select transcript
ENST00000327492.4NM_016272.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TOB2 yet. The test sequences your whole genome, so your data includes it all the same.

How TOB2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 22, with a bracket where TOB2 sits. TOB2 and 21 genes near it on chromosome 22, from 40,940,148 to 41,940,147.Chromosome 2222q13.2p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3341 Mb41.2 Mb41.4 Mb41.6 Mb41.8 MbRBX1: 40,951,277–40,973,539, forward strandRBX1EP300: 41,091,816–41,180,077, forward strandEP300L3MBTL2: 41,205,282–41,231,623, forward strandL3MBTL2CHADL: 41,229,256–41,241,000, reverse strandCHADLRANGAP1: 41,243,474–41,302,744, reverse strandRANGAP1ZC3H7B: 41,301,457–41,360,155, forward strandZC3H7BTEF: 41,367,333–41,399,326, forward strandTEFTOB2: 41,433,494–41,446,801, reverse strandTOB2ACO2: 41,447,830–41,529,273, forward strandACO2PHF5A: 41,448,895–41,468,713, reverse strandPHF5APOLR3H: 41,525,799–41,544,606, reverse strandPOLR3HCSDC2: 41,560,758–41,577,741, forward strandCSDC2PMM1: 41,576,886–41,595,275, reverse strandPMM1DESI1: 41,598,028–41,621,089, reverse strandDESI1XRCC6: 41,620,786–41,664,087, forward strandXRCC6SNU13: 41,666,627–41,690,504, reverse strandSNU13MEI1: 41,699,494–41,799,456, forward strandMEI1CCDC134: 41,800,321–41,832,178, forward strandCCDC134SREBF2: 41,833,029–41,907,308, forward strandSREBF2SHISA8: 41,906,316–41,915,129, reverse strandSHISA8TNFRSF13C: 41,922,032–41,926,806, reverse strandTNFRSF13CCENPM: 41,927,514–41,947,183, reverse strandCENPMDiagram of TOB2: 2 exons on the reverse strand of chromosome 22Exon 2: 41,433,494–41,437,407, 3,914 basesExon 1: 41,446,379–41,446,801, 423 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.3 kb of the gene's 13.3 kb; 1,035 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TOB2 gene: transducer of ERBB2, 2. Retrieved 18 October 2026, from https://dantelabs.com/genes/tob2

Vancouver

Dante Labs. TOB2 gene: transducer of ERBB2, 2 [Internet]. [cited 18 October 2026]. Available from: https://dantelabs.com/genes/tob2

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