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Gene

SMG1

SMG1 nonsense mediated mRNA decay associated PI3K related kinase

Summary

Cytogenetic location
16p12.3
Coordinates
Chromosome 16: 18,804,860–18,926,408 (GRCh38)
Exons
63 exons across 121.5 kb
Protein
3,661 amino acids
Also known as
LIP, KIAA0421, ATX
MANE Select transcript
ENST00000446231.7NM_015092.5
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMG1 yet. The test sequences your whole genome, so your data includes it all the same.

How SMG1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 16, with a bracket where SMG1 sits. SMG1 and 10 genes near it on chromosome 16, from 18,365,634 to 19,365,633.Chromosome 1616p12.3p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.318.4 Mb18.6 Mb18.8 Mb19 Mb19.2 MbNPIPA9: 18,358,086–18,379,331, reverse strandNPIPA9NOMO2: 18,417,325–18,562,211, reverse strandNOMO2RPS15A: 18,775,365–18,790,420, reverse strandRPS15A: 18,788,063–18,801,519, reverse strandARL6IP1: 18,791,609–18,801,572, reverse strandARL6IP1SMG1: 18,804,860–18,926,408, reverse strandSMG1TMC7: 18,983,928–19,063,947, forward strandTMC7COQ7: 19,067,564–19,082,190, forward strandCOQ7ITPRIPL2: 19,113,932–19,121,629, forward strandITPRIPL2SYT17: 19,167,971–19,268,334, forward strandSYT17CLEC19A: 19,285,731–19,322,145, forward strandCLEC19ADiagram of SMG1: 63 exons on the reverse strand of chromosome 16Exon 63: 18,804,860–18,809,646, 4,787 basesExon 62: 18,811,761–18,811,867, 107 basesExon 61: 18,811,948–18,812,127, 180 basesExon 60: 18,815,175–18,815,281, 107 basesExon 59: 18,815,440–18,815,651, 212 basesExon 58: 18,816,302–18,816,529, 228 basesExon 57: 18,817,291–18,817,470, 180 basesExon 56: 18,819,502–18,819,654, 153 basesExon 55: 18,828,031–18,828,168, 138 basesExon 54: 18,829,286–18,829,755, 470 basesExon 53: 18,829,926–18,830,115, 190 basesExon 52: 18,830,219–18,830,369, 151 basesExon 51: 18,832,940–18,833,166, 227 basesExon 50: 18,834,204–18,834,438, 235 basesExon 49: 18,834,892–18,835,164, 273 basesExon 48: 18,835,933–18,836,212, 280 basesExon 47: 18,836,360–18,836,532, 173 basesExon 46: 18,837,253–18,837,443, 191 basesExon 45: 18,838,014–18,838,232, 219 basesExon 44: 18,838,357–18,838,466, 110 basesExon 43: 18,838,551–18,838,689, 139 basesExon 42: 18,839,698–18,839,946, 249 basesExon 41: 18,841,565–18,841,794, 230 basesExon 40: 18,842,208–18,842,454, 247 basesExon 39: 18,845,429–18,845,651, 223 basesExon 38: 18,847,453–18,847,607, 155 basesExon 37: 18,847,816–18,848,033, 218 basesExon 36: 18,849,217–18,849,378, 162 basesExon 35: 18,849,949–18,850,126, 178 basesExon 34: 18,850,237–18,850,467, 231 basesExon 33: 18,852,067–18,852,205, 139 basesExon 32: 18,852,318–18,852,462, 145 basesExon 31: 18,853,583–18,853,867, 285 basesExon 30: 18,854,656–18,854,904, 249 basesExon 29: 18,858,170–18,858,290, 121 basesExon 28: 18,859,022–18,859,181, 160 basesExon 27: 18,859,556–18,859,703, 148 basesExon 26: 18,860,667–18,860,776, 110 basesExon 25: 18,863,650–18,863,851, 202 basesExon 24: 18,864,002–18,864,144, 143 basesExon 23: 18,866,621–18,866,775, 155 basesExon 22: 18,868,190–18,868,354, 165 basesExon 21: 18,868,523–18,868,719, 197 basesExon 20: 18,869,104–18,869,303, 200 basesExon 19: 18,869,854–18,869,994, 141 basesExon 18: 18,870,610–18,870,711, 102 basesExon 17: 18,870,801–18,870,888, 88 basesExon 16: 18,871,364–18,871,482, 119 basesExon 15: 18,872,184–18,872,345, 162 basesExon 14: 18,872,494–18,872,624, 131 basesExon 13: 18,876,124–18,876,393, 270 basesExon 12: 18,877,131–18,877,232, 102 basesExon 11: 18,879,495–18,879,719, 225 basesExon 10: 18,882,165–18,882,338, 174 basesExon 9: 18,884,070–18,884,167, 98 basesExon 8: 18,885,090–18,885,162, 73 basesExon 7: 18,885,541–18,885,666, 126 basesExon 6: 18,889,372–18,889,585, 214 basesExon 5: 18,890,863–18,890,921, 59 basesExon 4: 18,892,218–18,892,354, 137 basesExon 3: 18,896,052–18,896,207, 156 basesExon 2: 18,896,793–18,896,956, 164 basesExon 1: 18,925,950–18,926,408, 459 bases636055504540353025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 16.1 kb of the gene's 121.5 kb; 10,986 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SMG1 gene: SMG1 nonsense mediated mRNA decay associated PI3K related kinase. Retrieved 17 October 2026, from https://dantelabs.com/genes/smg1

Vancouver

Dante Labs. SMG1 gene: SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smg1

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