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Gene

SMCR8

SMCR8-C9orf72 complex subunit

Summary

Cytogenetic location
17p11.2
Coordinates
Chromosome 17: 18,315,293–18,328,056 (GRCh38)
Exons
2 exons across 12.8 kb
Protein
937 amino acids
Also known as
FLJ34716, DENND8A
MANE Select transcript
ENST00000406438.5NM_144775.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMCR8 yet. The test sequences your whole genome, so your data includes it all the same.

How SMCR8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where SMCR8 sits. SMCR8 and 19 genes near it on chromosome 17, from 17,821,675 to 18,821,674.Chromosome 1717p11.2p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.318 Mb18.2 Mb18.4 Mb18.6 Mb18.8 MbSREBF1: 17,810,399–17,837,035, reverse strandSREBF1TOM1L2: 17,843,507–17,972,470, reverse strandTOM1L2DRC3: 17,972,813–18,016,889, forward strandDRC3ATPAF2: 17,977,409–18,040,833, reverse strandATPAF2GID4: 18,039,371–18,068,405, forward strandGID4DRG2: 18,087,876–18,107,979, forward strandDRG2MYO15A: 18,108,756–18,179,802, forward strandMYO15AALKBH5: 18,183,034–18,209,954, forward strandALKBH5LLGL1: 18,225,542–18,244,876, forward strandLLGL1FLII: 18,244,782–18,260,420, reverse strandFLIIMIEF2: 18,259,527–18,266,552, forward strandMIEF2TOP3A: 18,271,428–18,315,025, reverse strandTOP3ASMCR8: 18,315,293–18,328,056, forward strandSMCR8SHMT1: 18,327,686–18,363,562, reverse strandSHMT1EVPLL: 18,377,674–18,389,652, forward strandEVPLLLGALS9C: 18,476,737–18,494,945, forward strandLGALS9CTBC1D28: 18,634,247–18,644,427, reverse strandTBC1D28FOXO3B: 18,667,629–18,682,314, reverse strandFOXO3BFBXW10: 18,744,026–18,779,349, forward strandFBXW10TVP23B: 18,781,111–18,806,772, forward strandTVP23BDiagram of SMCR8: 2 exons on the forward strand of chromosome 17Exon 1: 18,315,293–18,318,149, 2,857 basesExon 2: 18,322,617–18,328,056, 5,440 bases125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 8.3 kb of the gene's 12.8 kb; 2,814 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SMCR8 gene: SMCR8-C9orf72 complex subunit. Retrieved 17 October 2026, from https://dantelabs.com/genes/smcr8

Vancouver

Dante Labs. SMCR8 gene: SMCR8-C9orf72 complex subunit [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smcr8

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