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Gene

SF3B3

splicing factor 3b subunit 3

Summary

Cytogenetic location
16q22.1
Coordinates
Chromosome 16: 70,523,816–70,577,668 (GRCh38)
Exons
26 exons across 53.9 kb
Protein
1,217 amino acids
Also known as
SAP130, SF3b130, RSE1, KIAA0017
MANE Select transcript
ENST00000302516.10NM_012426.5
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SF3B3 yet. The test sequences your whole genome, so your data includes it all the same.

How SF3B3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 16, with a bracket where SF3B3 sits. SF3B3 and 14 genes near it on chromosome 16, from 70,050,742 to 71,050,741.Chromosome 1616q22.1p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.370.2 Mb70.4 Mb70.6 Mb70.8 Mb71 MbPDPR: 70,114,225–70,162,537, forward strandPDPRCLEC18C: 70,173,322–70,187,361, forward strandCLEC18CEXOSC6: 70,246,778–70,251,940, reverse strandEXOSC6AARS1: 70,251,983–70,289,707, reverse strandAARS1DDX19B: 70,289,663–70,335,992, forward strandDDX19B: 70,299,194–70,372,582, forward strandDDX19A: 70,346,861–70,379,987, forward strandDDX19AST3GAL2: 70,375,977–70,439,263, reverse strandST3GAL2FCSK: 70,454,398–70,480,275, forward strandFCSKCOG4: 70,480,567–70,523,582, reverse strandCOG4SF3B3: 70,523,816–70,577,668, forward strandSF3B3IL34: 70,579,868–70,661,556, forward strandIL34MTSS2: 70,661,204–70,686,086, reverse strandMTSS2VAC14: 70,687,436–70,801,178, reverse strandVAC14HYDIN: 70,802,084–71,230,735, reverse strandHYDINDiagram of SF3B3: 26 exons on the forward strand of chromosome 16Exon 1: 70,523,816–70,523,928, 113 basesExon 2: 70,526,587–70,526,726, 140 basesExon 3: 70,528,873–70,529,199, 327 basesExon 4: 70,530,745–70,530,917, 173 basesExon 5: 70,532,479–70,532,620, 142 basesExon 6: 70,535,308–70,535,420, 113 basesExon 7: 70,538,323–70,538,460, 138 basesExon 8: 70,539,104–70,539,207, 104 basesExon 9: 70,541,669–70,541,834, 166 basesExon 10: 70,544,438–70,544,533, 96 basesExon 11: 70,548,370–70,548,442, 73 basesExon 12: 70,554,446–70,554,597, 152 basesExon 13: 70,555,051–70,555,206, 156 basesExon 14: 70,556,179–70,556,334, 156 basesExon 15: 70,556,886–70,557,029, 144 basesExon 16: 70,560,469–70,560,591, 123 basesExon 17: 70,561,630–70,561,784, 155 basesExon 18: 70,563,876–70,564,050, 175 basesExon 19: 70,565,065–70,565,270, 206 basesExon 20: 70,565,368–70,565,524, 157 basesExon 21: 70,567,411–70,567,536, 126 basesExon 22: 70,568,283–70,568,495, 213 basesExon 23: 70,569,043–70,569,141, 99 basesExon 24: 70,570,006–70,570,149, 144 basesExon 25: 70,571,095–70,571,199, 105 basesExon 26: 70,571,673–70,577,668, 5,996 bases124681012141618202224265′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.7 kb of the gene's 53.9 kb; 3,654 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SF3B3 gene: splicing factor 3b subunit 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/sf3b3

Vancouver

Dante Labs. SF3B3 gene: splicing factor 3b subunit 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/sf3b3

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