Traits

Traits linked to RPL21

ribosomal protein L21

The Human Phenotype Ontology links 12 traits to RPL21, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the integument

Trait	How often it is seen
Dry hair	Always
Hair loss	Very often (80–99%)
Limited armpit hair	Very often (80–99%)
Sparse body hair	Very often (80–99%)
Sparse pubic hair	Very often (80–99%)
Sparse hair	Often (30–79%)
Slow-growing hair	Not recorded

Abnormality of head or neck

Trait	How often it is seen
Sparse scalp hair	Always
Sparse eyebrow	Very often (80–99%)
Sparse eyelashes	Very often (80–99%)
Sparse or absent eyelashes	Very often (80–99%)
Sparse or absent eyebrows	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to RPL21 and how often each is seen. Find out more at hpo.jax.org.

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