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Traits

Traits linked to PTPRC

protein tyrosine phosphatase receptor type C

The Human Phenotype Ontology links 15 traits to PTPRC, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of blood and blood-forming tissues

TraitHow often it is seen
B-cell lymphomaAlways
Decreased blood lymphocyte numberAlways
Increased total B cell countAlways
Low blood cell countAlways
Low T cell countAlways
Reduced total natural killer cell countAlways

Abnormal cellular phenotype

TraitHow often it is seen
Decreased circulating antibody levelAlways
Decreased circulating IgA concentrationAlways
Decreased circulating IgG concentrationAlways
Decreased circulating IgM concentrationAlways
Impaired phytohemagglutinin-induced T lymphocyte transformationAlways

Abnormality of the cardiovascular system

TraitHow often it is seen
Absence of lymph node germinal centerAlways
Enlarged liver and spleenAlways

Abnormality of the immune system

TraitHow often it is seen
Skin rashAlways

Laboratory abnormality

TraitHow often it is seen
FeverAlways

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to PTPRC and how often each is seen. Find out more at hpo.jax.org.

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