Skip to content
Use your HSA or FSA funds

Gene

PRSS22

serine protease 22

Summary

Cytogenetic location
16p13.3
Coordinates
Chromosome 16: 2,852,730–2,858,170 (GRCh38)
Exons
6 exons across 5.4 kb
Protein
317 amino acids
Also known as
TPSE1, hBSSP-4, BSSP-4, SP001LA
MANE Select transcript
ENST00000161006.8NM_022119.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PRSS22 yet. The test sequences your whole genome, so your data includes it all the same.

How PRSS22 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 16, with a bracket where PRSS22 sits. PRSS22 and 42 genes near it on chromosome 16, from 2,355,450 to 3,355,449.Chromosome 1616p13.3p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.32.4 Mb2.6 Mb2.8 Mb3 Mb3.2 MbCCNF: 2,429,394–2,458,913, forward strandCCNFTEDC2: 2,460,085–2,464,963, forward strandTEDC2NTN3: 2,471,286–2,474,145, forward strandNTN3TBC1D24: 2,475,051–2,509,671, forward strand: 2,496,032–2,520,218, forward strandATP6V0C: 2,513,713–2,520,218, forward strand: 2,513,965–2,527,955, forward strandAMDHD2: 2,520,340–2,531,422, forward strandAMDHD2CEMP1: 2,530,035–2,531,417, reverse strandCEMP1PDPK1: 2,537,969–2,603,190, forward strandPDPK1KCTD5: 2,682,516–2,709,030, forward strandKCTD5PRSS27: 2,712,419–2,721,270, reverse strandPRSS27SRRM2: 2,752,008–2,772,538, forward strandSRRM2ELOB: 2,771,413–2,777,320, reverse strandELOBPRSS33: 2,783,926–2,787,948, reverse strandPRSS33PRSS41: 2,798,470–2,805,304, forward strandPRSS41PRSS21: 2,817,130–2,826,304, forward strandPRSS21ZG16B: 2,830,162–2,839,585, forward strandZG16BPRSS22: 2,852,730–2,858,170, reverse strandPRSS22FLYWCH2: 2,882,868–2,903,099, forward strandFLYWCH2FLYWCH1: 2,911,599–2,951,208, forward strandFLYWCH1KREMEN2: 2,963,625–2,968,380, forward strandKREMEN2PKMYT1: 2,968,024–2,980,813, reverse strandPKMYT1PAQR4: 2,969,242–2,973,484, forward strandPAQR4GREP1: 2,988,256–3,002,295, forward strandGREP1: 3,004,132–3,004,859, forward strandCLDN9: 3,012,923–3,014,505, forward strandCLDN6: 3,014,705–3,020,071, reverse strandTNFRSF12A: 3,018,445–3,022,385, forward strandTHOC6: 3,022,541–3,027,755, forward strandHCFC1R1: 3,022,625–3,024,312, reverse strandBICDL2: 3,027,682–3,036,993, reverse strandMMP25: 3,046,062–3,060,729, forward strandMMP25IL32: 3,064,301–3,082,192, forward strandIL32ZSCAN10: 3,088,888–3,099,370, reverse strandZSCAN10ZNF205: 3,112,550–3,120,527, forward strandZNF205ZNF213: 3,129,777–3,142,804, forward strandZNF213OR1F1: 3,188,204–3,224,779, forward strandOR1F1ZNF200: 3,222,324–3,236,221, reverse strandZNF200MEFV: 3,240,392–3,256,954, reverse strandMEFVZNF263: 3,263,800–3,301,705, forward strandZNF263TIGD7: 3,298,390–3,305,729, reverse strandTIGD7ZNF75A: 3,305,385–3,320,003, forward strandZNF75ADiagram of PRSS22: 6 exons on the reverse strand of chromosome 16Exon 6: 2,852,730–2,853,329, 600 basesExon 5: 2,853,865–2,854,022, 158 basesExon 4: 2,855,574–2,855,851, 278 basesExon 3: 2,856,082–2,856,253, 172 basesExon 2: 2,856,822–2,856,848, 27 basesExon 1: 2,858,023–2,858,170, 148 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.4 kb of the gene's 5.4 kb; 954 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PRSS22 gene: serine protease 22. Retrieved 17 October 2026, from https://dantelabs.com/genes/prss22

Vancouver

Dante Labs. PRSS22 gene: serine protease 22 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/prss22

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test