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Gene

POU5F1

POU class 5 homeobox 1

Summary

Cytogenetic location
6p21.33
Coordinates
Chromosome 6: 31,164,337–31,170,682 (GRCh38)
Exons
5 exons across 6.3 kb
Protein
360 amino acids
Also known as
OCT3, Oct4, MGC22487, OCT-4, Oct3/4
Previous symbols
OTF3
MANE Select transcript
ENST00000259915.13NM_002701.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads POU5F1 yet. The test sequences your whole genome, so your data includes it all the same.

How POU5F1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 6, with a bracket where POU5F1 sits. POU5F1 and 45 genes near it on chromosome 6, from 30,667,510 to 31,667,509.Chromosome 66p21.33p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2730.8 Mb31 Mb31.2 Mb31.4 Mb31.6 MbDHX16: 30,652,469–30,673,059, reverse strandDHX16PPP1R18: 30,676,389–30,687,895, reverse strandNRM: 30,688,047–30,691,420, reverse strandNRMMDC1: 30,699,807–30,717,562, reverse strandMDC1TUBB: 30,717,435–30,725,538, forward strandTUBBFLOT1: 30,727,709–30,743,075, reverse strandFLOT1IER3: 30,743,199–30,744,555, reverse strandIER3DDR1: 30,876,421–30,900,978, forward strandDDR1GTF2H4: 30,907,517–30,914,119, forward strandVARS2: 30,914,205–30,928,614, forward strandVARS2SFTA2: 30,931,353–30,955,636, reverse strandSFTA2SFTA2-AS1: 30,934,523–30,938,824, forward strandSFTA2-AS1MUCL3: 30,940,973–30,954,221, forward strandMUCL3MUC21: 30,983,718–30,989,903, forward strandMUC21MUC22: 31,010,474–31,036,882, forward strandMUC22C6orf15: 31,111,223–31,112,582, reverse strandPSORS1C1: 31,114,750–31,140,092, forward strandCDSN: 31,115,087–31,120,446, reverse strandPSORS1C2: 31,137,534–31,139,721, reverse strandPSORS1C2CCHCR1: 31,142,439–31,158,238, reverse strandCCHCR1TCF19: 31,158,331–31,167,252, forward strandTCF19POU5F1: 31,164,337–31,170,682, reverse strandPOU5F1HLA-C: 31,268,746–31,272,171, reverse strandHLA-CHLA-B: 31,353,195–31,367,067, reverse strandHLA-BMICA: 31,399,784–31,415,315, forward strandMICAMICB: 31,494,881–31,511,124, forward strandMICBMCCD1: 31,528,962–31,530,232, forward strandMCCD1DDX39B: 31,530,217–31,542,451, reverse strandDDX39BATP6V1G2-DDX39B: 31,530,219–31,546,608, reverse strandATP6V1G2-DDX39BATP6V1G2: 31,544,444–31,548,427, reverse strandNFKBIL1: 31,546,870–31,558,829, forward strandLTA: 31,572,054–31,574,324, forward strandTNF: 31,575,558–31,578,336, forward strandTNFLTB: 31,580,525–31,582,522, reverse strandLST1: 31,581,065–31,588,911, forward strandNCR3: 31,588,895–31,593,217, reverse strandAIF1: 31,615,214–31,617,025, forward strandAIF1PRRC2A: 31,620,675–31,637,771, forward strand: 31,622,774–31,622,860, forward strand: 31,623,874–31,625,499, forward strandBAG6: 31,638,543–31,652,747, reverse strandAPOM: 31,652,416–31,658,214, forward strandAPOMC6orf47: 31,658,298–31,660,778, reverse strandGPANK1: 31,661,228–31,666,283, reverse strandCSNK2B: 31,665,227–31,670,343, forward strand: 31,666,102–31,673,546, forward strandDiagram of POU5F1: 5 exons on the reverse strand of chromosome 6Exon 5: 31,164,337–31,164,867, 531 basesExon 4: 31,165,128–31,165,286, 159 basesExon 3: 31,165,571–31,165,701, 131 basesExon 2: 31,165,927–31,166,047, 121 basesExon 1: 31,170,216–31,170,682, 467 bases543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.4 kb of the gene's 6.3 kb; 1,083 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). POU5F1 gene: POU class 5 homeobox 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/pou5f1

Vancouver

Dante Labs. POU5F1 gene: POU class 5 homeobox 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pou5f1

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