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Gene

PNLIP

pancreatic lipase

Summary

Cytogenetic location
10q25.3
Coordinates
Chromosome 10: 116,545,931–116,567,855 (GRCh38)
Exons
13 exons across 21.9 kb
Protein
465 amino acids
Also known as
PL
MANE Select transcript
ENST00000369221.2NM_000936.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PNLIP yet. The test sequences your whole genome, so your data includes it all the same.

How PNLIP is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 10, with a bracket where PNLIP sits. PNLIP and 9 genes near it on chromosome 10, from 116,056,893 to 117,056,892.Chromosome 1010q25.3p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.3116.2 Mb116.4 Mb116.6 Mb116.8 Mb117 MbGFRA1: 116,056,925–116,276,803, reverse strandGFRA1CCDC172: 116,324,388–116,380,029, forward strandCCDC172PNLIPRP3: 116,427,847–116,477,964, forward strandPNLIPRP3PNLIP: 116,545,931–116,567,855, forward strandPNLIPPNLIPRP1: 116,590,385–116,609,175, forward strandPNLIPRP1PNLIPRP2: 116,620,953–116,645,143, forward strandPNLIPRP2SPMIP5: 116,662,208–116,670,312, reverse strandSPMIP5HSPA12A: 116,671,192–116,850,251, reverse strandHSPA12AENO4: 116,849,481–116,911,788, forward strandENO4SHTN1: 116,881,477–117,126,586, reverse strandSHTN1Diagram of PNLIP: 13 exons on the forward strand of chromosome 10Exon 7: 1 known disease-causing siteExon 1: 116,545,931–116,545,958, 28 basesExon 2: 116,546,093–116,546,138, 46 basesExon 3: 116,547,294–116,547,448, 155 basesExon 4: 116,548,360–116,548,482, 123 basesExon 5: 116,551,098–116,551,232, 135 basesExon 6: 116,553,727–116,553,838, 112 basesExon 7: 116,555,178–116,555,297, 120 basesExon 8: 116,555,388–116,555,507, 120 basesExon 9: 116,556,000–116,556,118, 119 basesExon 10: 116,559,154–116,559,283, 130 basesExon 11: 116,560,416–116,560,524, 109 basesExon 12: 116,561,472–116,561,636, 165 basesExon 13: 116,567,735–116,567,855, 121 bases1510135′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.5 kb of the gene's 21.9 kb; 1,398 of those bases code for the protein.

How a genome test reads PNLIP

1

position in PNLIP where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 21.9 kb of PNLIP, introns included, not only the 1.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PNLIP gene: pancreatic lipase. Retrieved 17 October 2026, from https://dantelabs.com/genes/pnlip

Vancouver

Dante Labs. PNLIP gene: pancreatic lipase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pnlip

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