Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

PAXX

PAXX non-homologous end joining factor

Summary

Cytogenetic location
9q34.3
Coordinates
Chromosome 9: 136,992,422–136,993,976 (GRCh38)
Exons
7 exons across 1.6 kb
Protein
204 amino acids
Also known as
XLS
Previous symbols
C9orf142
MANE Select transcript
ENST00000371620.4NM_183241.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PAXX yet. The test sequences your whole genome, so your data includes it all the same.

How PAXX is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 9, with a bracket where PAXX sits. PAXX and 59 genes near it on chromosome 9, from 136,493,199 to 137,493,198.Chromosome 99q34.3p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.3136.6 Mb136.8 Mb137 Mb137.2 Mb137.4 MbNOTCH1: 136,494,433–136,546,048, reverse strandNOTCH1EGFL7: 136,658,284–136,672,684, forward strandEGFL7AGPAT2: 136,673,142–136,687,483, reverse strandAGPAT2DIPK1B: 136,712,302–136,724,742, forward strand: 136,738,167–136,748,453, reverse strandLCN10: 136,738,167–136,743,356, reverse strandLCN6: 136,744,017–136,748,531, reverse strandLCN6LCN8: 136,754,386–136,758,543, reverse strandLCN8LCN15: 136,759,634–136,766,255, reverse strandLCN15TMEM141: 136,791,303–136,793,317, forward strand: 136,791,379–136,800,595, forward strandCCDC183: 136,796,338–136,807,741, forward strandRABL6: 136,807,848–136,841,187, forward strandAJM1: 136,842,478–136,848,801, forward strandAJM1PHPT1: 136,847,994–136,851,043, forward strandPHPT1MAMDC4: 136,850,943–136,860,802, forward strandMAMDC4EDF1: 136,862,113–136,866,343, reverse strandEDF1TRAF2: 136,881,903–136,929,221, forward strandTRAF2FBXW5: 136,938,431–136,950,122, reverse strandC8G: 136,942,532–136,946,980, forward strandC8GLCN12: 136,949,391–136,956,535, forward strandPTGDS: 136,975,053–136,981,750, forward strand: 136,977,518–136,985,435, forward strandLCNL1: 136,981,904–136,986,410, forward strandLCNL1PAXX: 136,992,422–136,993,976, forward strandPAXXCLIC3: 136,994,608–136,996,729, reverse strandCLIC3ABCA2: 137,007,226–137,028,915, reverse strandABCA2FUT7: 137,030,174–137,032,825, reverse strand: 137,031,241–137,040,436, reverse strandNPDC1: 137,037,577–137,046,700, reverse strandNPDC1ENTPD2: 137,048,107–137,054,069, reverse strandSAPCD2: 137,062,127–137,070,593, reverse strandUAP1L1: 137,077,470–137,084,544, forward strandUAP1L1MAN1B1: 137,085,917–137,109,189, forward strandMAN1B1DPP7: 137,110,540–137,118,309, reverse strandDPP7GRIN1: 137,138,346–137,168,765, forward strandGRIN1LRRC26: 137,168,758–137,170,058, reverse strandLRRC26: 137,168,854–137,171,984, reverse strandTMEM210: 137,170,858–137,172,056, reverse strandTMEM210ANAPC2: 137,174,784–137,189,028, reverse strandSSNA1: 137,188,640–137,190,371, forward strandTPRN: 137,191,617–137,204,193, reverse strandTMEM203: 137,204,082–137,205,648, reverse strandNDOR1: 137,205,662–137,219,371, forward strandRNF229: 137,217,494–137,219,361, forward strandRNF208: 137,219,577–137,222,312, reverse strandCYSRT1: 137,225,174–137,226,315, forward strandRNF224: 137,226,908–137,229,640, forward strandRNF224SLC34A3: 137,230,757–137,236,555, forward strandTUBB4B: 137,241,278–137,243,713, forward strandTUBB4BCIMIP2A: 137,243,584–137,247,770, reverse strandSTPG3: 137,250,608–137,253,483, forward strandNELFB: 137,255,210–137,273,542, forward strandNELFBTOR4A: 137,274,854–137,282,641, forward strandNRARP: 137,299,631–137,302,271, reverse strandNRARPEXD3: 137,306,894–137,423,911, reverse strandEXD3NOXA1: 137,422,752–137,434,451, forward strandNOXA1ENTPD8: 137,434,362–137,441,881, reverse strandENTPD8NSMF: 137,447,570–137,459,576, reverse strandNSMFPNPLA7: 137,459,952–137,550,560, reverse strandPNPLA7Diagram of PAXX: 7 exons on the forward strand of chromosome 9Exon 1: 136,992,422–136,992,562, 141 basesExon 2: 136,992,640–136,992,700, 61 basesExon 3: 136,992,925–136,992,974, 50 basesExon 4: 136,993,053–136,993,243, 191 basesExon 5: 136,993,343–136,993,411, 69 basesExon 6: 136,993,580–136,993,664, 85 basesExon 7: 136,993,766–136,993,976, 211 bases12345675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.8 kb of the gene's 1.6 kb; 615 of those bases code for the protein.

Sequencing PAXX

19Moderate

How hard PAXX is to sequence with short reads, out of 100

Some of PAXX's exons sit where short reads can miss or misplace a change.

What adds to it: the share of PAXX's exons in each kind of hard region

  • Mappability0%
  • Homology0%
  • Shared with chrY0%
  • Reference coverage0%
  • Repeats10%
  • GC content80%

A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scored

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). PAXX gene: PAXX non-homologous end joining factor. Retrieved 20 October 2026, from https://dantelabs.com/genes/paxx

Vancouver

Dante Labs. PAXX gene: PAXX non-homologous end joining factor [Internet]. [cited 20 October 2026]. Available from: https://dantelabs.com/genes/paxx

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test