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Gene

MCL1

MCL1 apoptosis regulator, BCL2 family member

Summary

Cytogenetic location
1q21.2
Coordinates
Chromosome 1: 150,574,558–150,579,610 (GRCh38)
Exons
3 exons across 5.1 kb
Protein
350 amino acids
Also known as
BCL2L3, Mcl-1
MANE Select transcript
ENST00000369026.3NM_021960.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MCL1 yet. The test sequences your whole genome, so your data includes it all the same.

How MCL1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 1, with a bracket where MCL1 sits. MCL1 and 30 genes near it on chromosome 1, from 150,077,084 to 151,077,083.Chromosome 11q21.2p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44150.2 Mb150.4 Mb150.6 Mb150.8 Mb151 MbVPS45: 150,067,279–150,145,329, forward strandVPS45PLEKHO1: 150,149,183–150,164,720, forward strandPLEKHO1ANP32E: 150,217,463–150,236,202, reverse strandANP32ECA14: 150,257,069–150,265,078, forward strandAPH1A: 150,265,042–150,269,580, reverse strandAPH1AC1orf54: 150,268,034–150,281,744, forward strandC1orf54CIART: 150,282,527–150,287,093, forward strandCIARTMRPS21: 150,293,848–150,309,828, forward strandMRPS21PRPF3: 150,321,476–150,353,341, forward strandPRPF3RPRD2: 150,363,091–150,476,999, forward strandRPRD2TARS2: 150,487,325–150,507,614, forward strandTARS2ECM1: 150,507,989–150,515,000, forward strandECM1ADAMTSL4: 150,549,369–150,560,937, forward strandADAMTSL4MCL1: 150,574,558–150,579,610, reverse strandMCL1ENSA: 150,599,671–150,629,633, reverse strandENSAGOLPH3L: 150,638,727–150,697,222, reverse strandGOLPH3LHORMAD1: 150,698,059–150,720,895, reverse strandHORMAD1CTSS: 150,730,079–150,765,957, reverse strandCTSSCTSK: 150,794,880–150,809,577, reverse strandCTSKARNT: 150,808,617–150,876,771, reverse strandARNTCTXND2: 150,887,136–150,913,292, forward strandCTXND2SETDB1: 150,926,263–150,964,748, forward strandSETDB1CERS2: 150,959,099–150,977,396, reverse strandCERS2ANXA9: 150,981,321–150,996,077, forward strandANXA9MINDY1: 150,995,125–151,008,376, reverse strandMINDY1PRUNE1: 151,008,408–151,035,714, forward strandPRUNE1BNIPL: 151,036,321–151,047,720, forward strandBNIPLC1orf56: 151,047,746–151,051,986, forward strandC1orf56CDC42SE1: 151,050,242–151,070,325, reverse strandMLLT11: 151,054,177–151,069,544, forward strandGABPB2: 151,070,514–151,130,109, forward strandDiagram of MCL1: 3 exons on the reverse strand of chromosome 1Exon 3: 150,574,558–150,577,491, 2,934 basesExon 2: 150,578,244–150,578,491, 248 basesExon 1: 150,578,843–150,579,610, 768 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4 kb of the gene's 5.1 kb; 1,053 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MCL1 gene: MCL1 apoptosis regulator, BCL2 family member. Retrieved 17 October 2026, from https://dantelabs.com/genes/mcl1

Vancouver

Dante Labs. MCL1 gene: MCL1 apoptosis regulator, BCL2 family member [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mcl1

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