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Traits

Traits linked to IL21

interleukin 21

The Human Phenotype Ontology links 12 traits to IL21, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the digestive system

TraitHow often it is seen
Crohn's diseaseAlways
Inflammation of the large intestineAlways
Mucoid diarrheaAlways

Abnormal cellular phenotype

TraitHow often it is seen
Decreased circulating IgG concentrationAlways
Increased circulating IgE concentrationAlways

Growth abnormality

TraitHow often it is seen
Faltering weightAlways
Growth delayAlways

Abnormality of blood and blood-forming tissues

TraitHow often it is seen
Decreased class-switched memory B cell proportionAlways

Abnormality of head or neck

TraitHow often it is seen
Canker soreAlways

Abnormality of limbs

TraitHow often it is seen
Clubbing of fingersAlways

Abnormality of the immune system

TraitHow often it is seen
Recurrent respiratory infectionsAlways

Constitutional symptom

TraitHow often it is seen
FatigueAlways

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to IL21 and how often each is seen. Find out more at hpo.jax.org.

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