Trait

Airway hyperresponsiveness

An increased sensitivity of the airways to an inhaled constrictor agonist, a steeper slope of the dose-response curve, and a greater maximal response to the agonist.

HPO HP:0032933

Body system: Abnormality of the respiratory system

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/airway-hyperresponsiveness.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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8 genes linked to Airway hyperresponsiveness

Changes in these genes cause rare conditions in which Airway hyperresponsiveness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
ALOX5arachidonate 5-lipoxygenase	Not recorded	In 1 condition
CCL11C-C motif chemokine ligand 11	Not recorded	In 1 condition
HLA-Gmajor histocompatibility complex, class I, G	Not recorded	In 1 condition
HNMThistamine N-methyltransferase	Not recorded	In 1 condition
IL13interleukin 13	Not recorded	In 1 condition
MUC7mucin 7, secreted	Not recorded	In 1 condition
SCGB3A2secretoglobin family 3A member 2	Not recorded	In 1 condition
TNFtumor necrosis factor	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Functional respiratory abnormality

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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