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Gene

GPT

glutamic--pyruvic transaminase

Summary

Cytogenetic location
8q24.3
Coordinates
Chromosome 8: 144,504,140–144,507,172 (GRCh38)
Exons
11 exons across 3 kb
Protein
496 amino acids
Also known as
ALT1, ALT, GPT1, SGPT
MANE Select transcript
ENST00000394955.3NM_005309.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GPT yet. The test sequences your whole genome, so your data includes it all the same.

How GPT is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where GPT sits. GPT and 46 genes near it on chromosome 8, from 144,005,656 to 145,005,655.Chromosome 88q24.3p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.3144.2 Mb144.4 Mb144.6 Mb144.8 Mb145 MbPARP10: 143,977,151–144,019,930, reverse strandPARP10SPATC1: 144,012,275–144,047,114, forward strandSPATC1OPLAH: 144,051,265–144,064,091, reverse strandEXOSC4: 144,078,560–144,081,408, forward strand: 144,078,642–144,084,330, forward strandGPAA1: 144,082,337–144,093,149, forward strandCYC1: 144,095,039–144,097,525, forward strandSHARPIN: 144,097,513–144,108,124, reverse strandSHARPINMAF1: 144,103,112–144,107,618, forward strandMAF1WDR97: 144,107,726–144,118,328, forward strandWDR97HGH1: 144,137,774–144,140,851, forward strandHGH1MROH1: 144,147,975–144,262,470, forward strandMROH1BOP1: 144,262,045–144,291,453, reverse strandBOP1SCX: 144,266,446–144,268,481, forward strandSCXHSF1: 144,291,521–144,314,729, forward strandHSF1DGAT1: 144,314,584–144,326,916, reverse strandSCRT1: 144,330,565–144,336,503, reverse strandSLC52A2: 144,333,957–144,361,447, forward strandCATSPERQ: 144,352,219–144,354,954, reverse strandCATSPERQ: 144,353,228–144,355,609, reverse strandFBXL6: 144,355,427–144,359,376, reverse strandFBXL6ADCK5: 144,373,101–144,393,243, forward strandADCK5CPSF1: 144,393,229–144,409,864, reverse strandCPSF1SLC39A4: 144,409,742–144,416,894, reverse strandVPS28: 144,423,597–144,429,499, reverse strandVPS28TONSL: 144,428,763–144,444,488, reverse strandTONSLZFTRAF1: 144,447,345–144,462,908, reverse strandTMEM276-ZFTRAF1: 144,449,582–144,465,430, reverse strandTMEM276: 144,463,817–144,466,890, reverse strandKIFC2: 144,465,940–144,474,202, forward strandFOXH1: 144,473,412–144,475,873, reverse strandPPP1R16A: 144,475,989–144,502,126, forward strandGPT: 144,504,140–144,507,172, forward strandGPTSLC33A2: 144,508,263–144,511,317, forward strandSLC33A2RECQL4: 144,511,284–144,517,890, reverse strandRECQL4LRRC14: 144,517,957–144,526,244, forward strandLRRC14LRRC24: 144,522,385–144,527,608, reverse strandC8orf82: 144,525,733–144,529,132, reverse strandARHGAP39: 144,529,179–144,685,879, reverse strandZNF251: 144,720,515–144,756,417, reverse strandZNF251ZNF34: 144,770,441–144,788,684, reverse strandZNF34RPL8: 144,789,765–144,793,502, reverse strandRPL8ZNF517: 144,798,863–144,813,034, forward strandZNF517ZNF7: 144,826,894–144,848,546, forward strandZNF7COMMD5: 144,837,760–144,854,229, reverse strandCOMMD5ZNF250: 144,876,497–144,902,217, reverse strandZNF250ZNF16: 144,929,355–144,950,888, reverse strandZNF16Diagram of GPT: 11 exons on the forward strand of chromosome 8Exon 1: 144,504,140–144,504,466, 327 basesExon 2: 144,504,604–144,504,693, 90 basesExon 3: 144,504,771–144,504,879, 109 basesExon 4: 144,504,998–144,505,131, 134 basesExon 5: 144,505,246–144,505,489, 244 basesExon 6: 144,505,848–144,505,927, 80 basesExon 7: 144,505,995–144,506,131, 137 basesExon 8: 144,506,232–144,506,406, 175 basesExon 9: 144,506,501–144,506,656, 156 basesExon 10: 144,506,731–144,506,843, 113 basesExon 11: 144,506,910–144,507,172, 263 bases12345678910115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.8 kb of the gene's 3 kb; 1,491 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). GPT gene: glutamic--pyruvic transaminase. Retrieved 17 October 2026, from https://dantelabs.com/genes/gpt

Vancouver

Dante Labs. GPT gene: glutamic--pyruvic transaminase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gpt

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