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Gene

EXOC6B

exocyst complex component 6B

Summary

Cytogenetic location
2p13.2
Coordinates
Chromosome 2: 72,175,984–72,826,033 (GRCh38)
Exons
22 exons across 650.1 kb
Protein
811 amino acids
Also known as
KIAA0919
Previous symbols
SEC15L2, SEC15B
MANE Select transcript
ENST00000272427.11NM_015189.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads EXOC6B yet. The test sequences your whole genome, so your data includes it all the same.

How EXOC6B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where EXOC6B sits. EXOC6B and 13 genes near it on chromosome 2, from 71,525,934 to 73,476,083.Chromosome 22p13.2p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.372 Mb72.5 Mb73 MbDYSF: 71,453,495–71,686,763, forward strandDYSFCYP26B1: 72,129,238–72,148,430, reverse strandCYP26B1EXOC6B: 72,175,984–72,826,033, reverse strandEXOC6BSPR: 72,887,374–72,892,158, forward strandSPREMX1: 72,916,184–72,936,071, forward strandEMX1SFXN5: 72,939,248–73,075,619, reverse strandSFXN5RAB11FIP5: 73,073,382–73,156,721, reverse strandRAB11FIP5NOTO: 73,202,570–73,212,513, forward strandNOTOSMYD5: 73,214,222–73,227,229, forward strandSMYD5PRADC1: 73,228,008–73,233,262, reverse strandPRADC1CCT7: 73,233,420–73,253,282, forward strandCCT7FBXO41: 73,254,682–73,284,478, reverse strandEGR4: 73,290,927–73,293,721, reverse strandALMS1: 73,385,758–73,625,166, forward strandALMS1Diagram of EXOC6B: 22 exons on the reverse strand of chromosome 2Exon 20: 1 known disease-causing siteExon 19: 1 known disease-causing siteExon 9: 1 known disease-causing siteExon 22: 72,175,984–72,179,461, 3,478 basesExon 21: 72,184,075–72,184,187, 113 basesExon 20: 72,334,947–72,335,020, 74 basesExon 19: 72,379,729–72,379,870, 142 basesExon 18: 72,465,160–72,465,339, 180 basesExon 17: 72,480,616–72,480,750, 135 basesExon 16: 72,492,318–72,492,429, 112 basesExon 15: 72,495,430–72,495,539, 110 basesExon 14: 72,496,454–72,496,559, 106 basesExon 13: 72,498,454–72,498,551, 98 basesExon 12: 72,499,901–72,499,972, 72 basesExon 11: 72,513,132–72,513,252, 121 basesExon 10: 72,514,634–72,514,680, 47 basesExon 9: 72,515,043–72,515,126, 84 basesExon 8: 72,559,453–72,559,521, 69 basesExon 7: 72,575,492–72,575,668, 177 basesExon 6: 72,718,103–72,718,307, 205 basesExon 5: 72,731,007–72,731,052, 46 basesExon 4: 72,731,155–72,731,245, 91 basesExon 3: 72,733,071–72,733,118, 48 basesExon 2: 72,741,304–72,741,469, 166 basesExon 1: 72,825,798–72,826,033, 236 bases22201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.9 kb of the gene's 650.1 kb; 2,436 of those bases code for the protein.

How a genome test reads EXOC6B

4

positions in EXOC6B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 650.1 kb of EXOC6B, introns included, not only the 5.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). EXOC6B gene: exocyst complex component 6B. Retrieved 17 October 2026, from https://dantelabs.com/genes/exoc6b

Vancouver

Dante Labs. EXOC6B gene: exocyst complex component 6B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/exoc6b

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