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Gene

DEF8

differentially expressed in FDCP 8 homolog

Summary

Cytogenetic location
16q24.3
Coordinates
Chromosome 16: 89,948,755–89,968,060 (GRCh38)
Exons
13 exons across 19.3 kb
Protein
451 amino acids
Also known as
FLJ20186
MANE Select transcript
ENST00000563594.6NM_001242818.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DEF8 yet. The test sequences your whole genome, so your data includes it all the same.

How DEF8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 16, with a bracket where DEF8 sits. DEF8 and 20 genes near it on chromosome 16, from 89,458,408 to 90,458,407.Chromosome 1616q24.3p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.389.6 Mb89.8 Mb90 Mb90.2 Mb90.4 MbANKRD11: 89,267,619–89,490,706, reverse strandANKRD11SPG7: 89,490,719–89,557,768, forward strandSPG7RPL13: 89,560,637–89,567,834, forward strandRPL13CPNE7: 89,575,730–89,597,247, forward strandCPNE7DPEP1: 89,613,308–89,638,456, forward strandDPEP1CHMP1A: 89,640,816–89,657,738, reverse strandCHMP1ASPATA33: 89,657,740–89,671,287, forward strandSPATA33CDK10: 89,680,737–89,696,372, forward strandCDK10SPATA2L: 89,696,357–89,701,733, reverse strandSPATA2LVPS9D1: 89,707,128–89,721,879, reverse strandVPS9D1ZNF276: 89,720,400–89,740,925, forward strandZNF276FANCA: 89,726,683–89,816,977, reverse strandFANCASPIRE2: 89,818,179–89,871,320, forward strandSPIRE2TCF25: 89,873,214–89,913,627, forward strandTCF25MC1R: 89,912,119–89,920,977, forward strandMC1R: 89,919,165–89,936,092, forward strandTUBB3: 89,921,392–89,938,761, forward strandTUBB3DEF8: 89,948,755–89,968,060, forward strandDEF8DBNDD1: 90,004,648–90,019,890, reverse strandDBNDD1DRC4: 90,019,629–90,045,369, forward strandDRC4PRDM7: 90,056,566–90,092,072, reverse strandPRDM7Diagram of DEF8: 13 exons on the forward strand of chromosome 16Exon 1: 89,948,755–89,948,814, 60 basesExon 2: 89,949,417–89,949,513, 97 basesExon 3: 89,954,243–89,954,376, 134 basesExon 4: 89,955,169–89,955,266, 98 basesExon 5: 89,957,511–89,957,660, 150 basesExon 6: 89,959,014–89,959,155, 142 basesExon 7: 89,960,931–89,961,095, 165 basesExon 8: 89,961,737–89,961,864, 128 basesExon 9: 89,962,012–89,962,125, 114 basesExon 10: 89,963,363–89,963,443, 81 basesExon 11: 89,964,170–89,964,310, 141 basesExon 12: 89,964,466–89,964,575, 110 basesExon 13: 89,965,861–89,968,060, 2,200 bases124681012135′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.6 kb of the gene's 19.3 kb; 1,356 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). DEF8 gene: differentially expressed in FDCP 8 homolog. Retrieved 17 October 2026, from https://dantelabs.com/genes/def8

Vancouver

Dante Labs. DEF8 gene: differentially expressed in FDCP 8 homolog [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/def8

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