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Gene

C1RL

complement C1r subcomponent like

Summary

Cytogenetic location
12p13.31
Coordinates
Chromosome 12: 7,094,554–7,109,214 (GRCh38)
Exons
6 exons across 14.7 kb
Protein
487 amino acids
Also known as
C1r-LP, C1RL1
MANE Select transcript
ENST00000266542.9NM_016546.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads C1RL yet. The test sequences your whole genome, so your data includes it all the same.

How C1RL is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where C1RL sits. C1RL and 37 genes near it on chromosome 12, from 6,601,884 to 7,601,883.Chromosome 1212p13.31p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.336.8 Mb7 Mb7.2 Mb7.4 Mb7.6 Mb: 6,556,886–6,607,367, reverse strandCHD4: 6,570,081–6,614,982, reverse strandCHD4LPAR5: 6,618,835–6,636,444, reverse strandLPAR5ACRBP: 6,638,075–6,647,441, reverse strandACRBPING4: 6,650,282–6,663,180, reverse strandING4ZNF384: 6,665,037–6,689,572, reverse strandZNF384PIANP: 6,693,791–6,700,859, reverse strandPIANPCOPS7A: 6,724,014–6,732,462, forward strandCOPS7AMLF2: 6,747,986–6,768,932, reverse strandMLF2PTMS: 6,765,516–6,770,952, forward strandPTMSLAG3: 6,772,360–6,778,455, forward strandLAG3CD4: 6,786,858–6,820,807, forward strandCD4GPR162: 6,821,624–6,829,972, forward strandP3H3: 6,828,220–6,839,867, forward strandGNB3: 6,839,954–6,847,393, forward strandCDCA3: 6,844,723–6,852,353, reverse strandUSP5: 6,852,098–6,866,632, forward strandUSP5TPI1: 6,867,119–6,878,513, forward strandTPI1SPSB2: 6,870,934–6,889,358, reverse strandSPSB2LRRC23: 6,873,455–6,914,243, forward strandLRRC23ENO2: 6,913,745–6,923,970, forward strandENO2ATN1: 6,924,454–6,942,322, forward strandATN1C12orf57: 6,942,919–6,946,009, forward strandRNU7-1: 6,943,816–6,943,878, forward strandPTPN6: 6,946,417–6,961,316, forward strandPHB2: 6,965,327–6,970,841, reverse strandEMG1: 6,970,765–6,979,939, forward strandEMG1: 6,970,921–6,997,428, forward strandLPCAT3: 6,972,027–7,018,779, reverse strandLPCAT3C1S: 6,988,259–7,071,281, forward strandC1SC1R: 7,080,213–7,092,873, reverse strandC1RC1RL: 7,094,554–7,109,214, reverse strandC1RLRBP5: 7,115,736–7,128,891, reverse strandRBP5CLSTN3: 7,128,077–7,158,945, forward strandCLSTN3PEX5: 7,188,653–7,218,574, forward strandPEX5ACSM4: 7,304,072–7,328,719, forward strandACSM4CD163L1: 7,346,685–7,479,897, reverse strandCD163L1CD163: 7,469,417–7,503,911, reverse strandCD163Diagram of C1RL: 6 exons on the reverse strand of chromosome 12Exon 6: 7,094,554–7,097,163, 2,610 basesExon 5: 7,099,686–7,099,760, 75 basesExon 4: 7,099,901–7,100,026, 126 basesExon 3: 7,101,898–7,102,087, 190 basesExon 2: 7,108,251–7,108,479, 229 basesExon 1: 7,109,110–7,109,214, 105 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.3 kb of the gene's 14.7 kb; 1,464 of those bases code for the protein.

How a genome test reads C1RL

1

position in C1RL where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 14.7 kb of C1RL, introns included, not only the 3.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). C1RL gene: complement C1r subcomponent like. Retrieved 17 October 2026, from https://dantelabs.com/genes/c1rl

Vancouver

Dante Labs. C1RL gene: complement C1r subcomponent like [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/c1rl

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