Trait

Progressive peripheral neuropathy

HPO HP:0007133

Also called: Progressive polyneuropathy
Body system: Abnormality of the nervous system

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5 genes linked to Progressive peripheral neuropathy

Changes in these genes cause rare conditions in which Progressive peripheral neuropathy is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
COA8cytochrome c oxidase assembly factor 8	Very often (80–99%)	In 1 condition
ABCA1ATP binding cassette subfamily A member 1	Often (30–79%)	In 1 condition
ARSAarylsulfatase A	Often (30–79%)	In 4 conditions
PSAPprosaposin	Often (30–79%)	In 3 conditions
LYSTlysosomal trafficking regulator	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Peripheral neuropathy

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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