Trait

Itchy palm

Clinical name: Palmar pruritus

Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased sensation of itching over the palm(s) of the hand.

HPO HP:0031248

Body system: Abnormality of the integument

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/palmar-pruritus.json"
page <- fromJSON(url)
page$trait$name

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5 genes linked to Itchy palm

Changes in these genes cause rare conditions in which Itchy palm is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
CFTRCF transmembrane conductance regulator	Often (30–79%)	In 1 condition
ABCB11ATP binding cassette subfamily B member 11	Sometimes (5–29%)	In 1 condition
ABCB4ATP binding cassette subfamily B member 4	Sometimes (5–29%)	In 1 condition
ATP8B1ATPase phospholipid transporting 8B1	Sometimes (5–29%)	In 1 condition
NR1H4nuclear receptor subfamily 1 group H member 4	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Pruritis on hand

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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