Trait

High urine albumin levels

Clinical name: Moderate albuminuria

The presence of moderately increased concentrations of albumin in the urine, defined as and albumin-creatinine ratio (ACR) of 30 to 299 mg/gm (3.4 to 34 mg/mmol).

HPO HP:0012594

Also called: Microalbuminuria
Body system: Laboratory abnormality Abnormality of the genitourinary system

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10 genes linked to High urine albumin levels

Changes in these genes cause rare conditions in which High urine albumin levels is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
ABCC8ATP binding cassette subfamily C member 8	Always	In 2 conditions
SLC37A4solute carrier family 37 member 4	Always	In 1 condition
AMNamnion associated transmembrane protein	Often (30–79%)	In 1 condition
GCKglucokinase	Often (30–79%)	In 1 condition
INSinsulin	Often (30–79%)	In 1 condition
KCNJ11potassium inwardly rectifying channel subfamily J member 11	Often (30–79%)	In 1 condition
PDX1pancreatic and duodenal homeobox 1	Often (30–79%)	In 1 condition
STAT3signal transducer and activator of transcription 3	Often (30–79%)	In 1 condition
IER3IP1immediate early response 3 interacting protein 1	Sometimes (5–29%)	In 1 condition
MIA3MIA SH3 domain ER export factor 3	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Albuminuria

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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