Trait
Chronic active EBV infection
Chronic active Epstein-Barr virus (EBV) infection is an uncommon outcome of EBV infection and may present as a waxing and waning or fulminant syndrome. Unlike acute infectious mononucleosis, wherein EBV establishes lifelong infection and survives by maintaining a delicate balance with the host as a latent infection, in chronic active EBV infection the host-virus balance is disturbed.
Summary
- Also called
- Chronic active Epstein-Barr virus infection, Persistent Epstein-Barr virus infection, Recurrent Epstein-Barr virus infection
- Body system
- Abnormality of the immune system
Reference genomeGRCh38hg38
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Get my Genome Test4 genes linked to Chronic active EBV infection
Changes in these genes cause rare conditions in which Chronic active EBV infection is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| MAGT1magnesium transporter 1 | Always | In 1 condition |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Sometimes (5–29%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Sometimes (5–29%) | In 1 condition |
| IRF8interferon regulatory factor 8 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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