Trait
Hardened artery wall
Clinical name: Arteriosclerosis
Sclerosis (hardening) of the arteries with increased thickness of the wall of arteries as well as increased stiffness and a loss of elasticity.
Summary
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
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Get my Genome Test9 genes linked to Hardened artery wall
Changes in these genes cause rare conditions in which Hardened artery wall is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Very often (80–99%) | In 1 condition |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Very often (80–99%) | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Very often (80–99%) | In 1 condition |
| ERCC5ERCC excision repair 5, endonuclease | Very often (80–99%) | In 1 condition |
| HTRA1HtrA serine peptidase 1 | Often (30–79%) | In 1 condition |
| LIPAlipase A, lysosomal acid type | Often (30–79%) | In 1 condition |
| CATcatalase | Rarely (1–4%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Not recorded | In 1 condition |
| SMARCAL1SNF2 related chromatin remodeling annealing helicase 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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