Trait

Adrenocortical abnormality

HPO HP:0000849

Body system: Abnormality of the endocrine system

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5 genes linked to Adrenocortical abnormality

Changes in these genes cause rare conditions in which Adrenocortical abnormality is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
ABCD1ATP binding cassette subfamily D member 1	Often (30–79%)	In 1 condition
CDKN1Bcyclin dependent kinase inhibitor 1B	Often (30–79%)	In 1 condition
CDKN2Bcyclin dependent kinase inhibitor 2B	Often (30–79%)	In 1 condition
MEN1menin 1	Often (30–79%)	In 1 condition
PLXND1plexin D1	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Broader traits

Abnormal adrenal morphology

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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