Trait

Abnormal periungual morphology

An abnormality of the region around the nails of the fingers or toes.

HPO HP:0100803

Also called: Abnormality of the periungual region
Body system: Abnormality of the integument

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3 genes linked to Abnormal periungual morphology

Changes in these genes cause rare conditions in which Abnormal periungual morphology is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
LAMA3laminin subunit alpha 3	Often (30–79%)	In 1 condition
NFKB2nuclear factor kappa B subunit 2	Often (30–79%)	In 1 condition
NSDHLNAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL	Often (30–79%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Broader traits

Abnormality of the nail Regional abnormality of skin

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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