Trait
Abnormal CD4:CD8 ratio
Any abnormality in the relative amount of CD4+ and CD8+ T lymphocytes.
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Abnormal CD4:CD8 ratio, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test7 genes linked to Abnormal CD4:CD8 ratio
Changes in these genes cause rare conditions in which Abnormal CD4:CD8 ratio is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| RASGRP1RAS guanyl releasing protein 1 | Always | In 1 condition |
| WDR1WD repeat domain 1 | Often (30–79%) | In 1 condition |
| CIITAclass II major histocompatibility complex transactivator | Sometimes (5–29%) | In 1 condition |
| PGM3phosphoglucomutase 3 | Sometimes (5–29%) | In 1 condition |
| RFX5regulatory factor X5 | Sometimes (5–29%) | In 1 condition |
| RFXANKregulatory factor X associated ankyrin containing protein | Sometimes (5–29%) | In 1 condition |
| RFXAPregulatory factor X associated protein | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks