Trait
Webbed 2nd-4th toes
Clinical name: 2-4 toe syndactyly
Syndactyly with fusion of toes two to four.
Summary
- Also called
- Syndactyly of toes 2, 3 and 4, Syndactyly toes 2-4
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test5 genes linked to Webbed 2nd-4th toes
Changes in these genes cause rare conditions in which Webbed 2nd-4th toes is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| KDM6Blysine demethylase 6B | Always | In 1 condition |
| LEF1lymphoid enhancer binding factor 1 | Always | In 1 condition |
| IFT43intraflagellar transport 43 | Often (30–79%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| CKAP2Lcytoskeleton associated protein 2L | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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