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Gene

TNFRSF10A

TNF receptor superfamily member 10a

Summary

Cytogenetic location
8p21.3
Coordinates
Chromosome 8: 23,190,452–23,225,102 (GRCh38)
Exons
10 exons across 34.7 kb
Protein
468 amino acids
Also known as
DR4, Apo2, TRAILR-1, CD261, TRAILR1
MANE Select transcript
ENST00000221132.8NM_003844.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TNFRSF10A yet. The test sequences your whole genome, so your data includes it all the same.

How TNFRSF10A is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where TNFRSF10A sits. TNFRSF10A and 13 genes near it on chromosome 8, from 22,707,777 to 23,707,776.Chromosome 88p21.3p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.322.8 Mb23 Mb23.2 Mb23.4 Mb23.6 MbPEBP4: 22,710,102–23,000,000, reverse strandPEBP4RHOBTB2: 22,987,222–23,020,723, forward strandRHOBTB2TNFRSF10B: 23,020,133–23,069,121, reverse strandTNFRSF10B: 23,084,403–23,115,536, forward strandTNFRSF10C: 23,102,921–23,122,014, forward strandTNFRSF10CTNFRSF10D: 23,135,588–23,164,030, reverse strandTNFRSF10DTNFRSF10A: 23,190,452–23,225,102, reverse strandTNFRSF10ACHMP7: 23,243,630–23,266,156, forward strandCHMP7R3HCC1: 23,270,120–23,296,279, forward strandR3HCC1LOXL2: 23,296,897–23,425,328, reverse strandLOXL2ENTPD4: 23,385,783–23,457,722, reverse strandENTPD4SLC25A37: 23,528,859–23,654,350, forward strandSLC25A37NKX3-1: 23,678,697–23,682,953, reverse strandNKX3-1NKX2-6: 23,701,740–23,706,756, reverse strandNKX2-6Diagram of TNFRSF10A: 10 exons on the reverse strand of chromosome 8Exon 10: 23,190,452–23,192,013, 1,562 basesExon 9: 23,197,132–23,197,204, 73 basesExon 8: 23,199,266–23,199,448, 183 basesExon 7: 23,199,886–23,199,917, 32 basesExon 6: 23,200,505–23,200,600, 96 basesExon 5: 23,200,687–23,200,760, 74 basesExon 4: 23,201,808–23,201,919, 112 basesExon 3: 23,202,648–23,202,761, 114 basesExon 2: 23,212,116–23,212,212, 97 basesExon 1: 23,224,756–23,225,102, 347 bases10864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 34.7 kb; 1,407 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TNFRSF10A gene: TNF receptor superfamily member 10a. Retrieved 17 October 2026, from https://dantelabs.com/genes/tnfrsf10a

Vancouver

Dante Labs. TNFRSF10A gene: TNF receptor superfamily member 10a [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tnfrsf10a

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