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Gene

TEKT3

tektin 3

Summary

Cytogenetic location
17p12
Coordinates
Chromosome 17: 15,303,812–15,341,597 (GRCh38)
Exons
9 exons across 37.8 kb
Protein
490 amino acids
Also known as
FLJ32828
MANE Select transcript
ENST00000395930.6NM_031898.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TEKT3 yet. The test sequences your whole genome, so your data includes it all the same.

How TEKT3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where TEKT3 sits. TEKT3 and 10 genes near it on chromosome 17, from 14,822,705 to 15,822,704.Chromosome 1717p12p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.315 Mb15.2 Mb15.4 Mb15.6 Mb15.8 MbPMP22: 15,176,316–15,272,292, reverse strandPMP22TEKT3: 15,303,812–15,341,597, reverse strandTEKT3CDRT4: 15,433,937–15,475,733, reverse strandCDRT4TVP23C-CDRT4: 15,436,021–15,563,561, reverse strandTVP23C-CDRT4TVP23C: 15,502,264–15,563,595, reverse strandTVP23CFBXW10B: 15,565,484–15,619,704, reverse strandFBXW10B: 15,571,491–15,651,653, reverse strandTRIM16: 15,627,950–15,684,311, reverse strandTRIM16ZNF286A-TBC1D26: 15,699,552–15,745,940, forward strandZNF286A-TBC1D26ZNF286A: 15,699,577–15,720,787, forward strandZNF286ATBC1D26: 15,732,247–15,746,162, forward strandTBC1D26Diagram of TEKT3: 9 exons on the reverse strand of chromosome 17Exon 9: 15,303,812–15,304,152, 341 basesExon 8: 15,308,664–15,308,818, 155 basesExon 7: 15,312,259–15,312,481, 223 basesExon 6: 15,314,087–15,314,230, 144 basesExon 5: 15,319,077–15,319,147, 71 basesExon 4: 15,327,992–15,328,075, 84 basesExon 3: 15,331,007–15,331,614, 608 basesExon 2: 15,340,028–15,340,061, 34 basesExon 1: 15,341,518–15,341,597, 80 bases9876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.7 kb of the gene's 37.8 kb; 1,473 of those bases code for the protein.

Sequencing TEKT3

1

position in TEKT3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 37.8 kb of TEKT3, introns included, not only the 1.7 kb of exons.

ClinVar pathogenic variants (1)

The TEKT3 variants ClinVar classifies pathogenic or likely pathogenic for any condition, reviewed by at least one submitter with criteria, and the most reviewed of them. It is ClinVar's public record of the gene, never a result.

  • Likely pathogenic 1
VariantConditionsClinVar classificationReview status
NM_031898.3(TEKT3):c.734+1G>A (opens in a new tab)spermatogenic failure 81Likely pathogenic1 star out of 4 criteria provided, single submitter

Traits linked to TEKT3

The Human Phenotype Ontology lists these as features of the rare conditions TEKT3 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.18-8b139e39.

Cite this page

APA

Dante Labs. (n.d.). TEKT3 gene: tektin 3. Retrieved 18 October 2026, from https://dantelabs.com/genes/tekt3

Vancouver

Dante Labs. TEKT3 gene: tektin 3 [Internet]. [cited 18 October 2026]. Available from: https://dantelabs.com/genes/tekt3

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