Skip to content
Use your HSA or FSA funds

Gene

SH2D4B

SH2 domain containing 4B

Summary

Cytogenetic location
10q23.1
Coordinates
Chromosome 10: 80,537,902–80,646,560 (GRCh38)
Exons
8 exons across 108.7 kb
Protein
433 amino acids
MANE Select transcript
ENST00000646907.2NM_001388272.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SH2D4B yet. The test sequences your whole genome, so your data includes it all the same.

How SH2D4B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 10, with a bracket where SH2D4B sits. SH2D4B and 8 genes near it on chromosome 10, from 80,092,231 to 81,092,230.Chromosome 1010q23.1p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.380.2 Mb80.4 Mb80.6 Mb80.8 Mb81 MbTMEM254: 80,078,641–80,092,862, forward strandTMEM254PLAC9: 80,131,682–80,147,044, forward strandPLAC9ANXA11: 80,150,889–80,205,713, reverse strandANXA11MAT1A: 80,269,780–80,290,150, reverse strandMAT1ADYDC1: 80,336,105–80,356,760, reverse strandDYDC1DYDC2: 80,344,730–80,369,191, forward strandDYDC2PRXL2A: 80,406,443–80,437,115, forward strandPRXL2ATSPAN14: 80,453,875–80,533,178, forward strandTSPAN14SH2D4B: 80,537,902–80,646,560, forward strandSH2D4BDiagram of SH2D4B: 8 exons on the forward strand of chromosome 10Exon 1: 80,537,902–80,538,515, 614 basesExon 2: 80,570,154–80,570,316, 163 basesExon 3: 80,571,431–80,571,578, 148 basesExon 4: 80,588,630–80,588,777, 148 basesExon 5: 80,603,579–80,603,795, 217 basesExon 6: 80,609,424–80,609,551, 128 basesExon 7: 80,634,285–80,634,505, 221 basesExon 8: 80,643,993–80,646,560, 2,568 bases124685′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.2 kb of the gene's 108.7 kb; 1,302 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SH2D4B gene: SH2 domain containing 4B. Retrieved 17 October 2026, from https://dantelabs.com/genes/sh2d4b

Vancouver

Dante Labs. SH2D4B gene: SH2 domain containing 4B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sh2d4b

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test