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Gene

PPM1E

protein phosphatase, Mg2+/Mn2+ dependent 1E

Summary

Cytogenetic location
17q24.2
Coordinates
Chromosome 17: 58,755,854–58,985,179 (GRCh38)
Exons
7 exons across 229.3 kb
Protein
755 amino acids
Also known as
POPX1, KIAA1072, PP2CH, CaMKP-N
MANE Select transcript
ENST00000308249.4NM_014906.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PPM1E yet. The test sequences your whole genome, so your data includes it all the same.

How PPM1E is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where PPM1E sits. PPM1E and 15 genes near it on chromosome 17, from 58,370,517 to 59,370,516.Chromosome 1717q24.2p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.358.4 Mb58.6 Mb58.8 Mb59 Mb59.2 Mb: 58,345,206–58,417,595, reverse strandRNF43: 58,353,671–58,417,735, reverse strandRNF43HSF5: 58,420,167–58,488,408, reverse strandHSF5MTMR4: 58,489,529–58,517,905, reverse strandMTMR4SEPTIN4: 58,519,969–58,544,368, reverse strandSEPTIN4TEX14: 58,556,678–58,692,055, reverse strandTEX14IGBP1C: 58,660,424–58,692,055, reverse strandIGBP1CRAD51C: 58,692,569–58,735,611, forward strandRAD51CPPM1E: 58,755,854–58,985,179, forward strandPPM1ETRIM37: 58,982,633–59,106,921, reverse strandTRIM37SKA2: 59,109,857–59,155,260, reverse strandSKA2PRR11: 59,155,732–59,206,709, forward strandPRR11: 59,197,566–59,215,226, forward strandSMG8: 59,209,400–59,215,249, forward strandSMG8GDPD1: 59,220,467–59,275,970, forward strandGDPD1YPEL2: 59,331,591–59,401,729, forward strandYPEL2Diagram of PPM1E: 7 exons on the forward strand of chromosome 17Exon 1: 58,755,854–58,756,461, 608 basesExon 2: 58,955,649–58,955,767, 119 basesExon 3: 58,965,694–58,965,893, 200 basesExon 4: 58,969,539–58,969,727, 189 basesExon 5: 58,972,132–58,972,275, 144 basesExon 6: 58,972,832–58,972,925, 94 basesExon 7: 58,979,974–58,985,179, 5,206 bases1575′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.6 kb of the gene's 229.3 kb; 2,268 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PPM1E gene: protein phosphatase, Mg2+/Mn2+ dependent 1E. Retrieved 17 October 2026, from https://dantelabs.com/genes/ppm1e

Vancouver

Dante Labs. PPM1E gene: protein phosphatase, Mg2+/Mn2+ dependent 1E [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ppm1e

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