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Gene

PLP2

proteolipid protein 2

Summary

Cytogenetic location
Xp11.23
Coordinates
Chromosome X: 49,171,898–49,175,235 (GRCh38)
Exons
5 exons across 3.3 kb
Protein
152 amino acids
Also known as
A4, A4-LSB, MGC126187
MANE Select transcript
ENST00000376327.6NM_002668.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PLP2 yet. The test sequences your whole genome, so your data includes it all the same.

How PLP2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome X, with a bracket where PLP2 sits. PLP2 and 41 genes near it on chromosome X, from 48,673,567 to 49,673,566.Chromosome XXp11.23p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q2848.8 Mb49 Mb49.2 Mb49.4 Mb49.6 MbWAS: 48,676,593–48,691,431, forward strandWASSUV39H1: 48,695,554–48,709,556, forward strandSUV39H1GLOD5: 48,761,744–48,773,648, forward strandGLOD5GATA1: 48,783,122–48,794,311, forward strandGATA1HDAC6: 48,801,372–48,824,986, forward strandHDAC6ERAS: 48,826,513–48,830,138, forward strandERASPCSK1N: 48,831,088–48,835,632, reverse strandPCSK1NTIMM17B: 48,880,274–48,898,143, reverse strandPQBP1: 48,890,197–48,903,640, forward strandPQBP1SLC35A2: 48,903,180–48,911,958, reverse strandSLC35A2PIM2: 48,913,172–48,919,546, reverse strandPIM2OTUD5: 48,922,024–48,958,390, reverse strandOTUD5KCND1: 48,960,982–48,971,916, reverse strandKCND1GRIPAP1: 48,973,719–49,002,265, reverse strandGRIPAP1TFE3: 49,028,726–49,043,512, reverse strandTFE3CCDC120: 49,053,463–49,073,357, forward strandCCDC120PRAF2: 49,070,107–49,074,022, reverse strandPRAF2: 49,071,470–49,079,887, reverse strandWDR45: 49,074,431–49,101,203, reverse strandWDR45GPKOW: 49,112,941–49,123,750, reverse strandGPKOWMAGIX: 49,162,564–49,169,931, forward strandMAGIXPLP2: 49,171,898–49,175,235, forward strandPLP2PRICKLE3: 49,174,802–49,186,528, reverse strandPRICKLE3SYP: 49,187,807–49,200,218, reverse strandSYPCACNA1F: 49,205,063–49,233,371, reverse strandCCDC22: 49,235,444–49,250,526, forward strandCCDC22FOXP3: 49,250,436–49,264,800, reverse strandFOXP3: 49,258,343–49,270,477, reverse strandPPP1R3F: 49,269,771–49,301,468, forward strandPPP1R3FGAGE10: 49,303,645–49,319,844, forward strandGAGE10GAGE12J: 49,322,037–49,329,387, forward strandGAGE12JGAGE13: 49,331,575–49,338,952, forward strandGAGE13GAGE2E: 49,341,192–49,345,922, forward strandGAGE12B: 49,529,869–49,529,985, forward strandGAGE12BGAGE12C: 49,532,177–49,539,541, forward strandGAGE12CGAGE12D: 49,541,733–49,549,097, forward strandGAGE12DGAGE12E: 49,551,289–49,558,645, forward strandGAGE12EGAGE12F: 49,560,842–49,568,209, forward strandGAGE12G: 49,570,400–49,577,757, forward strandGAGE12H: 49,579,945–49,587,304, forward strandGAGE2A: 49,589,476–49,596,834, forward strandGAGE1: 49,599,020–49,608,538, forward strandGAGE1Diagram of PLP2: 5 exons on the forward strand of chromosome XExon 1: 49,171,898–49,172,096, 199 basesExon 2: 49,173,129–49,173,281, 153 basesExon 3: 49,173,388–49,173,483, 96 basesExon 4: 49,174,335–49,174,425, 91 basesExon 5: 49,174,672–49,175,235, 564 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.1 kb of the gene's 3.3 kb; 459 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PLP2 gene: proteolipid protein 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/plp2

Vancouver

Dante Labs. PLP2 gene: proteolipid protein 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/plp2

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