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Gene

MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

Summary

Cytogenetic location
19q13.2
Coordinates
Chromosome 19: 38,587,641–38,617,953 (GRCh38)
Exons
31 exons across 30.3 kb
Protein
821 amino acids
Also known as
HPK1
MANE Select transcript
ENST00000396857.7NM_001042600.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MAP4K1 yet. The test sequences your whole genome, so your data includes it all the same.

How MAP4K1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 19, with a bracket where MAP4K1 sits. MAP4K1 and 34 genes near it on chromosome 19, from 38,102,797 to 39,102,796.Chromosome 1919q13.2p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4338.2 Mb38.4 Mb38.6 Mb38.8 Mb39 MbSIPA1L3: 37,907,200–38,208,369, forward strandSIPA1L3DPF1: 38,211,006–38,229,729, reverse strandDPF1SPINT2: 38,244,035–38,292,615, forward strandSPINT2PPP1R14A: 38,250,856–38,256,615, reverse strand: 38,289,151–38,304,910, forward strandYIF1B: 38,303,558–38,317,273, reverse strandYIF1BC19orf33: 38,304,158–38,305,011, forward strandC19orf33KCNK6: 38,319,813–38,333,553, forward strandKCNK6CATSPERG: 38,335,775–38,370,943, forward strandPSMD8: 38,374,563–38,383,850, forward strandGGN: 38,384,267–38,388,274, reverse strandGGNSPRED3: 38,388,421–38,399,588, forward strandSPRED3TSLIG3C: 38,403,093–38,409,088, forward strandTSLIG3CRASGRP4: 38,409,051–38,426,305, reverse strandRASGRP4RYR1: 38,433,691–38,595,273, forward strandRYR1MAP4K1: 38,587,641–38,617,953, reverse strandMAP4K1EIF3K: 38,619,055–38,636,959, forward strandEIF3KACTN4: 38,647,515–38,731,589, forward strandACTN4CAPN12: 38,730,187–38,769,904, reverse strandCAPN12LGALS7: 38,770,968–38,773,542, reverse strandLGALS7LGALS7B: 38,789,191–38,791,754, forward strandLGALS7BLGALS4: 38,801,671–38,813,070, reverse strandLGALS4ECH1: 38,815,415–38,831,874, reverse strandECH1: 38,817,471–38,840,178, reverse strandHNRNPL: 38,836,370–38,852,347, reverse strandRINL: 38,867,830–38,878,275, reverse strandRINLSIRT2: 38,878,555–38,900,501, reverse strandSIRT2NFKBIB: 38,899,700–38,908,893, forward strandNFKBIBCCER2: 38,908,980–38,912,252, reverse strandCCER2SARS2: 38,915,265–38,930,779, reverse strandSARS2: 38,915,404–38,949,855, reverse strandMRPS12: 38,930,917–38,937,406, forward strandFBXO17: 38,941,401–38,976,773, reverse strandFBXO27: 38,990,714–39,033,773, reverse strandFBXO27ACP7: 39,083,913–39,111,497, forward strandACP7Diagram of MAP4K1: 31 exons on the reverse strand of chromosome 19Exon 31: 38,587,641–38,587,817, 177 basesExon 30: 38,593,282–38,593,337, 56 basesExon 29: 38,595,485–38,595,555, 71 basesExon 28: 38,595,640–38,595,729, 90 basesExon 27: 38,595,939–38,596,001, 63 basesExon 26: 38,596,312–38,596,486, 175 basesExon 25: 38,597,034–38,597,137, 104 basesExon 24: 38,597,326–38,597,384, 59 basesExon 23: 38,597,486–38,597,594, 109 basesExon 22: 38,599,925–38,599,985, 61 basesExon 21: 38,600,077–38,600,153, 77 basesExon 20: 38,601,441–38,601,525, 85 basesExon 19: 38,605,409–38,605,491, 83 basesExon 18: 38,605,568–38,605,730, 163 basesExon 17: 38,606,173–38,606,215, 43 basesExon 16: 38,607,864–38,607,911, 48 basesExon 15: 38,607,990–38,608,033, 44 basesExon 14: 38,608,112–38,608,170, 59 basesExon 13: 38,609,596–38,609,674, 79 basesExon 12: 38,609,909–38,610,025, 117 basesExon 11: 38,611,051–38,611,132, 82 basesExon 10: 38,611,243–38,611,305, 63 basesExon 9: 38,612,611–38,612,742, 132 basesExon 8: 38,613,880–38,613,952, 73 basesExon 7: 38,614,043–38,614,085, 43 basesExon 6: 38,614,245–38,614,292, 48 basesExon 5: 38,614,390–38,614,445, 56 basesExon 4: 38,616,195–38,616,259, 65 basesExon 3: 38,617,354–38,617,444, 91 basesExon 2: 38,617,568–38,617,625, 58 basesExon 1: 38,617,797–38,617,953, 157 bases313025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.6 kb of the gene's 30.3 kb; 2,466 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MAP4K1 gene: mitogen-activated protein kinase kinase kinase kinase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/map4k1

Vancouver

Dante Labs. MAP4K1 gene: mitogen-activated protein kinase kinase kinase kinase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/map4k1

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