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Gene

SIRT2

sirtuin 2

Summary

Cytogenetic location
19q13.2
Coordinates
Chromosome 19: 38,878,560–38,899,618 (GRCh38)
Exons
16 exons across 21.1 kb
Protein
389 amino acids
Previous symbols
SIR2L
MANE Select transcript
ENST00000249396.12NM_012237.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads SIRT2 yet. The test sequences your whole genome, so your data includes it all the same.

How SIRT2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 19, with a bracket where SIRT2 sits. SIRT2 and 34 genes near it on chromosome 19, from 38,389,089 to 39,389,088.Chromosome 1919q13.2p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4338.4 Mb38.6 Mb38.8 Mb39 Mb39.2 MbSPRED3: 38,388,421–38,399,588, forward strandSPRED3TSLIG3C: 38,403,093–38,409,088, forward strandTSLIG3CRASGRP4: 38,409,051–38,426,305, reverse strandRASGRP4RYR1: 38,433,691–38,595,273, forward strandRYR1MAP4K1: 38,587,641–38,619,161, reverse strandMAP4K1EIF3K: 38,619,055–38,636,959, forward strandEIF3KACTN4: 38,647,515–38,731,589, forward strandACTN4CAPN12: 38,730,187–38,769,904, reverse strandCAPN12LGALS7: 38,770,968–38,773,542, reverse strandLGALS7LGALS7B: 38,789,191–38,791,754, forward strandLGALS4: 38,801,671–38,813,070, reverse strandLGALS4ECH1: 38,815,415–38,831,874, reverse strandECH1: 38,817,471–38,840,178, reverse strandHNRNPL: 38,836,370–38,852,347, reverse strandHNRNPLRINL: 38,867,830–38,878,275, reverse strandRINLSIRT2: 38,878,560–38,899,618, reverse strandSIRT2NFKBIB: 38,899,700–38,908,893, forward strandNFKBIBCCER2: 38,908,980–38,912,252, reverse strandCCER2SARS2: 38,915,265–38,930,779, reverse strandSARS2: 38,915,404–38,949,855, reverse strandMRPS12: 38,930,917–38,937,406, forward strandFBXO17: 38,941,401–38,976,773, reverse strandFBXO27: 38,990,714–39,033,773, reverse strandFBXO27ACP7: 39,083,913–39,111,497, forward strandACP7PAK4: 39,125,728–39,182,816, forward strandPAK4NCCRP1: 39,196,917–39,201,884, forward strandNCCRP1SYCN: 39,202,825–39,204,283, reverse strandSYCNIFNL3: 39,243,455–39,245,250, reverse strandIFNL3IFNL4: 39,246,314–39,248,856, reverse strandIFNL4IFNL2: 39,268,396–39,270,188, forward strandIFNL2IFNL1: 39,296,407–39,298,673, forward strandIFNL1LRFN1: 39,306,566–39,320,966, reverse strandLRFN1GMFG: 39,328,351–39,342,372, reverse strandGMFGSAMD4B: 39,342,404–39,385,710, forward strandSAMD4BPAF1: 39,385,629–39,391,154, reverse strandPAF1Diagram of SIRT2: 16 exons on the reverse strand of chromosome 19Exon 16: 38,878,560–38,879,310, 751 basesExon 15: 38,879,434–38,879,500, 67 basesExon 14: 38,879,632–38,879,702, 71 basesExon 13: 38,880,685–38,880,736, 52 basesExon 12: 38,880,821–38,880,897, 77 basesExon 11: 38,881,100–38,881,155, 56 basesExon 10: 38,881,432–38,881,491, 60 basesExon 9: 38,883,627–38,883,756, 130 basesExon 8: 38,889,087–38,889,155, 69 basesExon 7: 38,889,689–38,889,745, 57 basesExon 6: 38,889,855–38,889,961, 107 basesExon 5: 38,890,103–38,890,144, 42 basesExon 4: 38,893,414–38,893,527, 114 basesExon 3: 38,893,819–38,893,867, 49 basesExon 2: 38,898,379–38,898,425, 47 basesExon 1: 38,899,506–38,899,618, 113 bases16141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.9 kb of the gene's 21.1 kb; 1,170 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SIRT2 gene: sirtuin 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/sirt2

Vancouver

Dante Labs. SIRT2 gene: sirtuin 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sirt2

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