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Gene

IL22

interleukin 22

Summary

Cytogenetic location
12q15
Coordinates
Chromosome 12: 68,248,242–68,253,604 (GRCh38)
Exons
6 exons across 5.4 kb
Protein
179 amino acids
Also known as
ILTIF, IL-21, zcyto18, IL-TIF, IL-D110, TIFa, TIFIL-23, IL-22, MGC79382, MGC79384
MANE Select transcript
ENST00000538666.6NM_020525.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads IL22 yet. The test sequences your whole genome, so your data includes it all the same.

How IL22 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 12, with a bracket where IL22 sits. IL22 and 6 genes near it on chromosome 12, from 67,750,923 to 68,750,922.Chromosome 1212q15p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3367.8 Mb68 Mb68.2 Mb68.4 Mb68.6 MbIFNG: 68,154,768–68,159,748, reverse strandIFNGIL26: 68,201,349–68,225,813, reverse strandIL26IL22: 68,248,242–68,253,604, reverse strandIL22SAXO6: 68,272,443–68,332,396, reverse strandSAXO6RAP1B: 68,610,410–68,671,901, forward strandRAP1BNUP107: 68,686,951–68,745,809, forward strandNUP107SLC35E3: 68,746,080–68,793,974, forward strandSLC35E3Diagram of IL22: 6 exons on the reverse strand of chromosome 12Exon 6: 68,248,242–68,248,876, 635 basesExon 5: 68,251,513–68,251,578, 66 basesExon 4: 68,252,504–68,252,647, 144 basesExon 3: 68,252,764–68,252,829, 66 basesExon 2: 68,253,263–68,253,494, 232 basesExon 1: 68,253,583–68,253,604, 22 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.2 kb of the gene's 5.4 kb; 540 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). IL22 gene: interleukin 22. Retrieved 17 October 2026, from https://dantelabs.com/genes/il22

Vancouver

Dante Labs. IL22 gene: interleukin 22 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/il22

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